Recombinant Mouse T-Lymphocyte Activation Antigen CD80 (CD80), C-His

Mouse T-Lymphocyte Activation Antigen CD80 is an activation antigen expressed on T lymphocytes, involved in immune response regulation. In mouse experiments, CD80 is used to study immune cell activation and immune response regulation mechanisms. CD80 serves as a costimulatory molecule that interacts with CD28 on T cells to provide essential signals for T cell activation, proliferation, and differentiation. This interaction is crucial for the initiation and maintenance of effective immune responses against pathogens and tumors. In the context of autoimmune diseases, overexpression of CD80 has been implicated in the exacerbation of immune reactions, leading to tissue damage. Therefore, targeting CD80-CD28 interactions has emerged as a potential therapeutic strategy to modulate immune responses in various clinical settings, including transplantation, inflammation, and cancer immunotherapy.