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Recombinant Bovine Peptidyl-Prolyl Cis-Trans Isomerase FKBP3 (FKBP3), N-His
Product Overview
BioVenic's Recombinant Bovine Peptidyl-Prolyl Cis-Trans Isomerase FKBP3 (FKBP3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 28.8 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Bovine peptidyl-prolyl cis-trans isomerase FKBP3 is a member of the immunophilin protein family, which plays a role in immunoregulation and cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds immunosuppressants like FK506 and rapamycin, as well as other proteins such as histone deacetylases, transcription factor YY1, Casein Kinase II, and nucleolin. It is particularly important for its higher affinity to rapamycin, suggesting its role in immunosuppression by this drug.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.