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Recombinant Canine Distemper Virus Fusion Glycoprotein F0 (F)
Product Overview
BioVenic's Recombinant Canine Distemper Virus Fusion Glycoprotein F0 (F) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 73.0 kDa.
Specifications
Target Information
Canine distemper virus fusion glycoprotein F0 (F) is a key protein in the canine distemper virus (CDV) that facilitates viral entry into host cells by mediating membrane fusion. Initially synthesized as an inactive precursor, F0, it trimerizes and is cleaved into two subunits, F1 and F2, which are crucial for its function. The F protein is activated by furin cleavage, transitioning from a prefusion to a postfusion conformation, which is associated with membrane merging and viral entry. This protein is also a major target for immune responses, making it significant for vaccine development and understanding viral pathogenesis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.