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Mouse Anti-Canine IL-33 Monoclonal Antibody

Cat. No.VD12Q12

Product TypeAnimal-targeted Antibodies

Size 100 µL

Product Overview

BioVenic mouse anti-canine IL-33 monoclonal antibody is specific for canine IL-33. It was produced in mouse hybridoma and protein A purified. It can be applied to ELISA assay.

Specifications

Application ELISA
Clonality Monoclonal Antibody
Clone D8Q1
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine IL-33
Isotype IgG1
Immunogen Recombinant Canine IL-33 Protein
Purification Protein A Purified
Purity ≥ 95% (SDS-PAGE)
Conjugation Unconjugated
Buffer Phosphate buffered saline
Physical State Liquid

Target Information

Canine Interleukin-33 (IL-33) is a cytokine that plays a critical role in inflammation and immune response in canines. Studies indicate that IL-33 expression is upregulated in the keratinocytes of dogs in response to the serine protease derived from house dust mites, via the activation of protease-activated receptor-2. This suggests that IL-33 might play a role in the inflammatory response and itchiness associated with dermatitis in dogs caused by house dust mites. Further research is needed to clarify the clinical implications of these findings and develop potential therapies.

Target Canine IL-33
Target Synonym interleukin-33
Gene ID 403810
UniProt ID O97863

Shipping and Storage

This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Miller, Ashley M. "Role of IL-33 in inflammation and disease." Journal of inflammation 8 (2011): 1-12.
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