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Mouse Anti-Sheep CD14 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for sheep CD14. It can be applied to ELISA, IHC, FCM and IP assays of sheep CD14.
Specifications
Target Information
Sheep CD14 is a crucial component of the immune system, serving as a multifunctional lipopolysaccharide receptor. It is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 plays a significant role in the innate immune response by binding to lipopolysaccharide (LPS) in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. This interaction is essential for the recognition of bacterial pathogens and the initiation of inflammatory responses. Additionally, CD14 can bind apoptotic cells and is involved in various immune processes, including allergic, inflammatory, and infectious responses.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.