Mouse Anti-Canine Profilin 1 Monoclonal Antibody

Canine profilin 1 is an actin-binding protein that plays a critical role in cytoskeletal dynamics, cell signaling, and is implicated in various diseases, including cancer and neurological disorders. It is essential for cellular processes such as motility, migration, and synaptic plasticity, with its expression being nearly ubiquitous across different cell and tissue types in dogs. Profilin 1's interaction with actin is crucial for processes like lamellipodium formation in migrating cells and myelination in the peripheral nervous system. Mutations in Profilin 1 have been linked to amyotrophic lateral sclerosis (ALS), highlighting its importance in motor neuron function and survival. This protein is also involved in early brain development and vascular health, making it a significant target for research in canine health and disease management.