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Mouse Anti-Porcine Proopiomelanocortin (POMC) Monoclonal Antibody

Cat. No.VD8N254

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for proopiomelanocortin. It is affinity purified by protein A. It can be applied to WB, IHC, IF/ICC and ELISA assays of proopiomelanocortin.

Specifications

Application WB; IHC; IF/ICC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N67
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Proopiomelanocortin
Isotype IgG1
Immunogen Recombinant protein of proopiomelanocortin
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine proopiomelanocortin (POMC) is a precursor protein found in pigs that is central to the regulation of various physiological processes, including the stress response, immune function, and energy homeostasis. POMC is synthesized primarily in the pituitary gland and the hypothalamus and serves as a precursor for several bioactive peptides, such as adrenocorticotropic hormone (ACTH), melanocyte-stimulating hormones (MSH), and endorphins. The diverse roles of POMC-derived peptides make this precursor protein a target of interest in veterinary medicine and comparative biology. ACTH, for instance, is a key hormone in the regulation of the adrenal cortex, influencing glucocorticoid production and playing a critical role in the body's response to stress. MSH peptides are involved in pigmentation and immune modulation, while endorphins contribute to pain management and the perception of pleasure.

Target Proopiomelanocortin
Target Synonym Beta-endorphin; Beta LPH lipotropin gamma
Gene ID 396863
UniProt ID P01192

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Millington, George WM. "The role of proopiomelanocortin (POMC) neurones in feeding behaviour." Nutrition & metabolism 4 (2007): 1-16.
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