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Mouse Anti-Porcine Superoxide Dismutase 1 (SOD1) Monoclonal Antibody

Cat. No.VD8N217

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for superoxide dismutase 1. It is affinity purified by protein A. It can be applied to WB, IHC, IF/ICC, FC and ELISA assays of superoxide dismutase 1.

Specifications

Application WB; IHC; IF/ICC; FC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N30
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Superoxide Dismutase 1
Isotype IgG2
Immunogen Recombinant protein of superoxide dismutase 1
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine superoxide dismutase 1 (pSOD1) is a vital antioxidant enzyme that plays a critical role in the defense mechanism against oxidative stress in pigs. It is responsible for dismutating superoxide radicals into oxygen and hydrogen peroxide, thereby protecting cells from the damaging effects of reactive oxygen species (ROS) that can lead to cellular damage and various diseases. pSOD1 is found in various tissues, including the liver, heart, and skeletal muscle, where it is particularly important for maintaining cellular integrity and function. The enzyme operates as a homodimer, with each subunit containing a copper and a zinc ion at its active site, which are essential for its catalytic activity.

Target Superoxide Dismutase 1
Target Synonym IPOA
Gene ID 397036
UniProt ID P04178

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Blander, Gil, et al. "Superoxide dismutase 1 knock-down induces senescence in human fibroblasts." Journal of Biological Chemistry 278.40 (2003): 38966-38969.
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