This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Anti Wesselsbron Virus (WSLV) NS1 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for wesselsbron virus NS1. It is affinity purified by ion-exchange assays of wesselsbron virus NS1.
Specifications
Target Information
Wesselsbron virus (WSLV) nonstructural protein 1 (NS1) is a pivotal component in the viral life cycle of the wesselsbron virus, which belongs to the family Coronaviridae. This protein is involved in multiple stages of viral replication, including modulation of host immune responses, regulation of viral transcription, and replication. The NS1 protein of Wesselsbron Virus has been shown to possess both RNA-binding and ubiquitin ligase activities, which are crucial for its role in viral pathogenesis. It can interfere with the host's interferon response, thereby aiding the virus in evading the innate immune system. Additionally, NS1 is implicated in the assembly of the viral replication complex, highlighting its significance in the viral replication process.
Shipping and Storage
This product is shipped with dry ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Faye, Martin, et al. "Development of real-time molecular assays for the detection of Wesselsbron virus in Africa." Microorganisms 10.3 (2022): 550.; Ji, Zhu-xing, et al. "NS1: a Key protein in the "game" between influenza A virus and host in innate immunity." Frontiers in cellular and infection microbiology 11 (2021): 670177.