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Rabbit Anti-Streptococcus Group A Monoclonal Antibody
Product Overview
BioVenic rabbit monoclonal antibody is specific for Streptococcus group A. It is affinity purified by protein A. It can be applied to ELISA of Streptococcus group A.
Specifications
Target Information
Streptococcus group A, commonly referred to as group A streptococcus (GAS), is a significant bacterial pathogen responsible for a range of infections in humans, from minor skin infections to life-threatening conditions like necrotizing fasciitis and streptococcal toxic shock syndrome. The "Streptococcus Group A Strep Carbohydrate" likely refers to the carbohydrate structures on the surface of GAS, known as the group A carbohydrate (GAC) or the Lancefield antigen. The GAC is a polysaccharide that forms part of the bacterial cell wall and serves as a key virulence factor. It helps the bacteria evade the host immune system by acting as a molecular shield, and it also plays a role in the pathogen's adherence to host tissues.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Rush, Jeffrey S., et al. "The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes." Journal of Biological Chemistry 292.47 (2017): 19441-19457.