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Rabbit Anti-Rift Valley Fever Virus Glycoprotein N Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rift valley fever virus glycoprotein N. It is affinity purified by protein A. It can be applied to ELISA of rift valley fever virus glycoprotein N.
Specifications
Target Information
The rift valley fever virus (RVFV) glycoprotein N, commonly referred to as Gc, is a critical surface glycoprotein that, along with the glycoprotein C (Gn), forms the envelope of the virus. Glycoprotein N is essential for the virus's ability to bind to host cell receptors and mediate fusion, which are the initial steps in the infection process. This glycoprotein is a significant target for vaccine development due to its role in host immune response activation. It is capable of inducing neutralizing antibodies that can prevent the virus from binding to host cells, thereby providing immunity against RVFV. The structure and function of Glycoprotein N are of particular interest to researchers, as understanding its interaction with host cell receptors could lead to the design of effective vaccines and antiviral treatments.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Phoenix, Inaia, et al. "Mutational analysis of the Rift Valley fever virus glycoprotein precursor proteins for Gn protein expression." Viruses 8.6 (2016): 151.