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Rabbit Anti-Monkeypox and Vaccinia A13 Polyclonal Antibody

Cat. No.VD7N177

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for monkeypox and vaccinia A13. It is affinity purified by protein A. It can be applied to SPR, WB, ELISA and IF assays of monkeypox and vaccinia A13.

Specifications

Application SPR; WB; ELISA; IF
Clonality Polyclonal
Classification Primary Antibody
Clone L16N5
Host Rabbit
Target Species Virus
Species Reactivity Virus
Specificity A13 Membrane Protein of Monkeypox Virus and Vaccinia Virus
Isotype IgG
Immunogen Live vaccinia virus
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Proclin 300
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

The A13 membrane protein is a conserved and essential component found in both the monkeypox virus and the vaccinia virus, which are members of the Orthopoxvirus genus. This protein is a virion-associated membrane protein that plays a significant role in the virus's life cycle, particularly in the assembly and egress of the virus from the host cell. A13 is implicated in the formation of the virus's envelope and may also contribute to immune evasion by interfering with host cell signaling pathways. As a target for antiviral development, the A13 Membrane Protein offers a unique opportunity due to its conserved nature across different poxviruses. Targeting A13 could potentially lead to the development of broad-spectrum antivirals effective against various members of the Orthopoxvirus genus. Understanding the molecular mechanisms by which A13 functions within the virus could reveal vulnerabilities that can be exploited therapeutically. The structural and functional characterization of A13 is therefore of great interest to researchers seeking to combat poxvirus infections and to enhance our preparedness against emerging or re-emerging viral threats.

Target A13 Membrane Protein of Monkeypox Virus and Vaccinia Virus
Target Synonym VACV; monkeypox virus; Protein P8; A13L; vaccinia virus; smallpox virus; VACV virion membrane proteins; Virion membrane protein A13; VACWR132
Taxonomy ID 10244

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Taha, Taha Y., et al. "Design and optimization of a monkeypox virus specific serological assay." Pathogens 12.3 (2023): 396.
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