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Chicken Anti-Bovine Neurofilament H Polyclonal Antibody

Cat. No.VD7N391

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic chicken polyclonal antibody is specific for bovine neurofilament H. It can be applied to ICC, IHC and WB of bovine neurofilament H.

Specifications

Application ICC; IHC; WB
Clonality Polyclonal
Classification Primary Antibody
Clone L13N64
Host Chicken
Target Species Bovine
Species Reactivity Bovine; Chicken
Specificity Neurofilament H Protein
Isotype IgY
Immunogen Purified bovine neurofilament H protein
Purity > 90%
Conjugation Unconjugated
Preservative and Stabilizer 10mM Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Neurofilament H (NF-H), also known as the heavy neurofilament subunit, is a vital structural protein found in the neuronal axons of the nervous system. NF-H, along with other neurofilament proteins, provides mechanical support and contributes to the axonal diameter and stability. It plays a critical role in maintaining the cytoskeleton and is involved in axonal transport. NF-H is a significant biomarker for various neurological disorders, including amyotrophic lateral sclerosis (ALS) and neuropathies.

Target Neurofilament H Protein
Target Synonym 200 kDa neurofilament protein antibody; CMT2CC antibody
Taxonomy ID 35360
Gene ID 4744
UniProt ID P12036

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Dong, Dennis L-Y., et al. "Cytoplasmic O-GlcNAc modification of the head domain and the KSP repeat motif of the neurofilament protein neurofilament-H." Journal of Biological Chemistry 271.34 (1996): 20845-20852.
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