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Mouse Anti-Canine Mast Cell Tryptase Monoclonal Antibody

Cat. No.VD11N207

Product TypeAnimal-targeted Antibodies

Size 200 μg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine mast cell tryptase. It can be applied to WB, ICC/IF, IHC and ELISA assays of canine mast cell tryptase.

Specifications

Application WB; ICC/IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone S18N2
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Mast Cell Tryptase
Isotype IgG1
Immunogen Recombinant protein of mast cell tryptase
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Canine mast cell tryptase is a serine protease enzyme stored in the secretory granules of mast cells and plays a significant role in inflammation, tissue remodeling, and angiogenesis. It is released when mast cells degranulate in response to allergen-bound IgE or non-immunological stimuli, contributing to local or systemic effects. In veterinary medicine, tryptase has been associated with canine mast cell tumors (MCTs), which are one of the most common cutaneous malignancies in dogs. Tryptase's activity is implicated in tumor angiogenesis, influencing tumor growth, invasion, and metastasis.

Target Canine Mast Cell Tryptase
Target Synonym Mastocytoma protease
UniProt ID P19236

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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