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Mouse Anti-Chicken Poly ADP-Ribose Polymerase (PARP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for chicken poly polymerase. It can be applied to WB assay of chicken poly polymerase.
Specifications
Target Information
Poly (ADP-ribose) polymerase (PARP) is a family of enzymes that are integral to the cellular response to DNA damage. PARP enzymes, particularly PARP-1, play a pivotal role in the detection and repair of DNA strand breaks by catalyzing the transfer of ADP-ribose units from NAD+ to target proteins, including themselves. PARP activation leads to the recruitment of DNA repair proteins to the site of damage, facilitating the base excision repair (BER) pathway and other repair mechanisms. This activity is crucial for maintaining genomic stability and preventing mutations that can lead to cancer.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lingner, Joachim, et al. "Purification and characterization of poly (A) polymerase from Saccharomyces cerevisiae." Journal of Biological Chemistry 266.14 (1991): 8741-8746.