Mouse Anti-Porcine Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) Monoclonal Antibody

Porcine ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) is an ortholog of the human protein involved in cellular differentiation and development. This protein has been associated with the regulation of the mitochondrial network, playing a role in maintaining the balance between mitochondrial fusion and fission, which is crucial for cellular energy metabolism and cellular health. Mutations in the human GDAP1L1 gene have been linked to Charcot-Marie-Tooth disease, a hereditary motor and sensory neuropathy, indicating the importance of this protein in nerve function. In pigs, GDAP1L1 may serve as a valuable model for studying the mechanisms of neurodegenerative diseases and for developing therapeutic strategies due to the conservation of this protein across species. The broad expression of GDAP1L1 in various systems, including the nervous, respiratory, and visual systems, underscores its multifaceted role in cellular biology. Understanding the function of porcine GDAP1L1 can provide insights into its human counterpart and contribute to the development of treatments for diseases associated with its dysfunction.