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Mouse Anti-Porcine Sarcomeric Mitochondrial Creatine Kinase (sMtCK) Monoclonal Antibody

Cat. No.VD8N150

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine sarcomeric mitochondrial creatine kinase. It can be applied to WB assay of porcine sarcomeric mitochondrial creatine kinase.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone G4N13
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Sarcomeric Mitochondrial Creatine Kinase
Isotype IgG
Immunogen Purified recombinant porcine sarcomeric mitochondrial creatine kinase protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Sarcomeric mitochondrial creatine kinase (sMtCK), also known as mitsCAMK, is an isoform of the creatine kinase enzyme that is specifically localized to the mitochondria of skeletal muscle cells. This unique enzyme plays a critical role in energy metabolism by catalyzing the phosphotransferase reaction, which helps maintain the ATP/ADP ratio necessary for muscle contraction and relaxation. sMtCK is particularly important in situations requiring rapid and high-energy phosphate supply, such as during intense muscle activity. It functions to replenish ATP levels by transferring a phosphate group from phosphocreatine to ADP, thus regenerating ATP from ADP in the mitochondrial matrix.

Target Porcine Sarcomeric Mitochondrial Creatine Kinase
Target Synonym CKMT2
Gene ID 733602
UniProt ID Q2HYU1

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Khuchua, Zaza A., et al. "Octamer formation and coupling of cardiac sarcomeric mitochondrial creatine kinase are mediated by charged N-terminal residues." Journal of Biological Chemistry 273.36 (1998): 22990-22996.
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