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Mouse Anti-Porcine Suppressor of Cytokine Signaling 3 (SOCS3) Monoclonal Antibody

Cat. No.VD12N504

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine suppressor of cytokine signaling 3. It is purified by affinity chromatography. It can be applied to WB, IHC and IF assays of porcine suppressor of cytokine signaling 3.

Specifications

Application WB; IHC; IF
Clonality Monoclonal
Classification Primary Antibody
Clone M6N10
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Suppressor of Cytokine Signaling 3
Immunogen Recombinant protein of suppressor of cytokine signaling 3
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Porcine Suppressor of Cytokine Signaling 3 (SOCS3) is a key regulator of cytokine signaling, playing a crucial role in modulating immune responses and inflammation. SOCS3 inhibits signaling pathways downstream of cytokine receptors, particularly those involving the JAK/STAT pathway. It interacts with receptors such as IL-6, leptin, and erythropoietin, and is involved in the negative regulation of cytokine-induced signaling. In porcine models, SOCS3 has been shown to downregulate pro-inflammatory responses and is implicated in viral infections, such as porcine circovirus type 2.

Target Porcine Suppressor of Cytokine Signaling 3
Target Synonym SOCS3
Gene ID 493186
UniProt ID E5EZY0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Zhu, Xuejiao, et al. "Suppressor of cytokine signaling 3 plays an important role in porcine circovirus type 2 subclinical infection by downregulating proinflammatory responses." Scientific Reports 6.1 (2016): 32538.
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