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Mouse Anti-Porcine Aminomethyltransferase (AMT) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for aminomethyltransferase. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of aminomethyltransferase.
Specifications
Target Information
Porcine aminomethyltransferase (pAMT) is an enzyme that catalyzes the transfer of an aminomethyl group from S-adenosylmethionine to acceptor molecules, a reaction that is integral to the biosynthesis of glycine and the activation of folate. This protein plays a pivotal role in one-carbon metabolism, which is essential for various biological processes, including DNA synthesis, methylation, and the production of certain amino acids. pAMT is highly conserved across species, reflecting its importance in maintaining cellular homeostasis. In pigs, this enzyme contributes to the metabolic pathways that support growth, development, and the overall health of the animal. Its activity is regulated by various factors, including the availability of substrates and the cellular demand for one-carbon units.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Okamura-Ikeda, Kazuko, et al. "Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system: implications for recognition of lipoyl protein substrate, disease-related mutations, and reaction mechanism." Journal of Biological Chemistry 285.24 (2010): 18684-18692.