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Mouse Anti-Porcine Regulator of G-Protein Signaling 4 (RGS4) Monoclonal Antibody

Cat. No.VD8N409

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic mouse monoclonal antibody is specific for regulator of G-protein signaling 4. It is affinity purified by protein G. It can be applied to WB and ELISA assays of regulator of G-protein signaling 4.

Specifications

Application WB; ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone G9N9

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Regulator of G-Protein Signaling 4

Isotype IgG1

Immunogen Recombinant protein of regulator of G-protein signaling 4

Purification Protein G Purified

Concentration 1600 μg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3

Physical State Liquid

Target Information

Porcine regulator of G-protein signaling 4 (pRGS4) is a member of the regulator of G-protein signaling (RGS) protein family, which are key modulators of G-protein coupled receptor (GPCR) signaling pathways. pRGS4 plays a critical role in the desensitization and termination of GPCR signaling, thereby ensuring proper cellular responses to various stimuli in pigs. This protein functions as a GTPase-activating protein (GAP) for Gα subunits, accelerating the hydrolysis of GTP to GDP, which in turn inactivates the G protein and its downstream signaling cascade. pRGS4 is involved in the regulation of a variety of physiological processes, including immune responses, cell migration, and differentiation.

Target Regulator of G-Protein Signaling 4

Target Synonym RGP4; RGS4

Gene ID 100157437

UniProt ID F1S215

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Carbone, Alexandra M., et al. "Regulator of G-protein signaling-4 attenuates cardiac adverse remodeling and neuronal norepinephrine release-promoting free fatty acid receptor FFAR3 signaling." International journal of molecular sciences 23.10 (2022): 5803.