Mouse Anti-Rift Valley Fever Virus Glycoprotein N Monoclonal Antibody

The rift valley fever virus (RVFV) glycoprotein N, commonly referred to as Gc, is a critical surface glycoprotein that, along with the glycoprotein C (Gn), forms the envelope of the virus. Glycoprotein N is essential for the virus's ability to bind to host cell receptors and mediate fusion, which are the initial steps in the infection process. This glycoprotein is a significant target for vaccine development due to its role in host immune response activation. It is capable of inducing neutralizing antibodies that can prevent the virus from binding to host cells, thereby providing immunity against RVFV. The structure and function of Glycoprotein N are of particular interest to researchers, as understanding its interaction with host cell receptors could lead to the design of effective vaccines and antiviral treatments.