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Rabbit Anti-Borrelia burgdorferi P35 Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for Borrelia burgdorferi P35. It is affinity purified by protein A. It can be applied to ELISA and WB of Borrelia burgdorferi P35.
Specifications
Target Information
Borrelia burgdorferi p35 is a protein associated with the bacterium's survival and pathogenicity, particularly known for its role in the persistence of the infection within the host. This protein is a part of the B. burgdorferi's regulatory network and is implicated in the bacterium's ability to adapt to various environmental conditions, including those encountered during its transmission between ticks and mammals. The p35 protein is thought to be involved in the regulation of gene expression within the bacterium, affecting its virulence and the expression of other outer surface proteins, such as OspA and OspC. This regulatory function is crucial for the bacterium's transition between its tick vector and mammalian hosts, as it allows B. burgdorferi to modulate its surface proteins in response to different host environments.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hellwage, Jens, et al. "The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi." Journal of Biological Chemistry 276.11 (2001): 8427-8435.