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Rabbit Anti-Borrelia burgdorferi P35 Polyclonal Antibody

Cat. No.VD7N114

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for Borrelia burgdorferi P35. It is affinity purified by protein A. It can be applied to ELISA and WB of Borrelia burgdorferi P35.

Specifications

Application ELISA; WB
Clonality Polyclonal
Classification Primary Antibody
Clone L12N62
Host Rabbit
Target Species Bacteria
Species Reactivity Bacteria
Specificity Borrelia burgdorferi P35 Protein
Isotype IgG
Immunogen Recombinant Borrelia burgdorferi P35 protein
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.01% Sodium Azide
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Physical State Liquid

Target Information

Borrelia burgdorferi p35 is a protein associated with the bacterium's survival and pathogenicity, particularly known for its role in the persistence of the infection within the host. This protein is a part of the B. burgdorferi's regulatory network and is implicated in the bacterium's ability to adapt to various environmental conditions, including those encountered during its transmission between ticks and mammals. The p35 protein is thought to be involved in the regulation of gene expression within the bacterium, affecting its virulence and the expression of other outer surface proteins, such as OspA and OspC. This regulatory function is crucial for the bacterium's transition between its tick vector and mammalian hosts, as it allows B. burgdorferi to modulate its surface proteins in response to different host environments.

Target Borrelia burgdorferi P35 Protein
Taxonomy ID 139
UniProt ID P70848

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Hellwage, Jens, et al. "The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi." Journal of Biological Chemistry 276.11 (2001): 8427-8435.
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