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Rabbit Anti-Canine Clusterin (CLU) Polyclonal Antibody-[FITC]

Cat. No.VD11N901

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine clusterin. It is antigen affinity purified. It can be applied to WB, IHC and IF/ICC assays of canine clusterin.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone J17N28
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Clusterin
Isotype IgG
Immunogen Recombinant protein of clusterin
Purification Antigen Affinity Purified
Conjugation FITC
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine clusterin, also known as apolipoprotein J, is a multifunctional glycoprotein involved in various biological processes. It is a disulfide-linked heterodimeric protein primarily known for its role in aiding protein folding and preventing aggregation of non-native proteins. Clusterin acts as an extracellular chaperone, protecting cells against apoptosis and cytolysis by complement. It is expressed in multiple tissues, including the kidneys, where it may serve as a biomarker for renal tubular injury. In dogs, elevated urinary clusterin levels have been associated with acute kidney injury, indicating its potential as an early diagnostic marker.

Target Canine Clusterin
Target Synonym CLU
UniProt ID P25473

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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