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Dairy Cattle Mastitis Solution

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To help veterinary researchers and animal health researchers address the major challenge of dairy cattle husbandry, BioVenic provides customized dairy mastitis solutions based on quantitative real-time PCR technology that can detect multiple pathogens simultaneously.

Custom Solution for Dairy Cattle Mastitis

Mastitis, a multifactorial inflammatory disease of the breast, is primarily attributed to intramammary infections (IMI). Bacterial culprits, including Escherichia coli, Staphylococcus aureus, and Streptococcus spp., along with fungal agents, commonly contribute to this condition. Our one-stop solution is designed to concurrently identify more than 19 pathogens and β-lactamase resistance genes, offering a comprehensive diagnostic solution for bovine mastitis. Additionally, we offer the flexibility to customize PCR kits to detect specific pathogens based on your unique requirements.

Table. 1 Bovine Mastitis-related Pathogens Detected

Escherichia coli Staphylococcus aureus Streptococcus uberis Streptococcus agalactiae Trueperella pyogenes
Mycoplasma bovis Serratia marcescens Corynebacterium bovis Coagulase-negative Staphylococci Streptococcus dysgalactiae
Klebsiella pneumoniae Mycoplasma spp. Anaeroplasma spp. Bacillus β-lactamase resistance genes
Enterococcus spp. Candida albicans Pasteurella multocida Acinetobacter baumannii Acinetobacter baumannii

Background of Dairy Cattle Mastitis

The United States stands as the world's second-largest milk producer, following closely behind the 27 EU countries in the global dairy market. As of 2022, the nation boasts around 9.4 million dairy cows, generating a staggering $57.3 billion in revenue solely from milk sales. Despite these impressive figures, a concerning global trend reveals that one-third of the world's 220 million dairy cows grapple with varying degrees of mastitis. This condition, which inflicts substantial economic losses, not only diminishes milk production and quality but also extends the postpartum estrus cycle of dairy cows. Consequently, it hampers productive performance, compounding the financial impact on the industry. In the United States, mastitis in dairy cows exacts an annual toll of approximately $1.7-2 billion on the dairy sector.

Common clinical mastitis symptoms in dairy cows include udder redness, swelling, and heat, along with changes in milk color and consistency, indicative of an inflammatory response. However, subclinical mastitis is asymptomatic. The California mastitis test (CMT), somatic cell count (SCC), and microbial culture help identify this condition, while PCR detection technology is also employed. Maintaining a hygienic environment is crucial for prevention, involving regular disinfection of cow sheds and heightened precautions during high mastitis seasons. Treatment typically involves antibiotics like penicillin, and ampicillin, but may lead to antibiotic resistance and residue issues. Early diagnosis is an important method to deal with this problem and effectively control the spread of mastitis in dairy cows.

Fig. 1 Dairy Cattle Mastitis.Fig. 1 Dairy Cattle Mastitis.1

Comparison of Different Mastitis Diagnostic Protocols

Microbial culture, CMT, and SCC tests are traditional methods for identifying dairy cow mastitis, while fluorescence quantitative PCR is a rapid and accurate detection technology. Our comparative analysis of various testing methods aims to assist you in selecting the optimal solution for diagnosing dairy cow mastitis.

Comparison of Different Mastitis Diagnostic Protocols

Features of BioVenic Custom Multiplex Quantitative Real-time PCR Kit

BioVenic Multiplex Quantitative Real-time PCR Kit is meticulously crafted for the swift and precise detection of mastitis in dairy cows. With results available in just a few hours, addressing the prevention and treatment of dairy cow mastitis becomes an expedited and efficient process. Moreover, the custom kit is adaptable to diverse laboratory settings, empowering veterinary researchers to achieve early diagnosis and providing guidance for medication.

Swift

Swift

The entire process is completed within a mere 1.5 hours.

Precision

Precision

  • Exceptional specificity.
  • Simultaneous detection of all pathogens.
  • Capability to identify low-concentration pathogens.

Convenience

Convenience

  • Applicable for DHI sample detection.
  • Monitoring of medication processes and effectiveness.
  • Minimal requirements for testing environments and experimental personnel.
  • Continuous access to professional technical support and solutions.

Our advanced solution for dairy cattle mastitis not only aids in reducing the risk of allergy and drug resistance stemming from antibiotic residues but also contributes to the overall health and well-being of dairy cows. For further details about the kit or additional information on dairy cow mastitis, please do not hesitate to contact us. Let's collaborate in safeguarding the health of dairy cows, ensuring a prosperous and sustainable future.

Referencess

  1. Li, Xiaoping, et al. "Alternatives to antibiotics for treatment of mastitis in dairy cows." Frontiers in Veterinary Science 10 (2023): 1160350.
  2. Barlow, John. "Mastitis therapy and antimicrobial susceptibility: a multispecies review with a focus on antibiotic treatment of mastitis in dairy cattle." Journal of mammary gland biology and neoplasia 16 (2011): 383-407.
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