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Mouse Anti-Porcine Ras Homolog Family Member A (RHOA) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for ras homolog family member A. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of ras homolog family member A.
Specifications
Target Information
Porcine ras homolog family member A (pRHOA), also known as Ras-related C3 botulinum toxin substrate A, is a small GTPase protein that is part of the Rho family, which is crucial in the regulation of actin cytoskeleton dynamics in pigs. pRHOA plays a pivotal role in various cellular processes, including cell migration, adhesion, and cytokinesis. As a molecular switch, pRHOA cycles between an active GTP-bound state and an inactive GDP-bound state, which allows it to regulate multiple signaling pathways. Its activity is tightly controlled by guanine nucleotide exchange factors (GEFs), GTPase-activating proteins (GAPs), and GDP dissociation inhibitors (GDIs).
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Schmidt, Sissel Ida, et al. "RhoA signaling in neurodegenerative diseases." Cells 11.9 (2022): 1520.