Rabbit Anti-Bovine Aspartate Aminotransferase (GOT1) Polyclonal Antibody

Bovine aspartate aminotransferase (AST), also known as GOT, is an enzyme that plays a pivotal role in the transfer of amino groups from aspartate to alpha-ketoglutarate, producing glutamate and oxaloacetate. This enzyme is crucial in various metabolic pathways, including the urea cycle and the citric acid cycle. AST is found in high concentrations in tissues with high metabolic activity, such as the heart, liver, and skeletal muscle. In cattle, AST is an important biomarker for liver function and can be used to diagnose conditions such as liver damage or inflammation. It is also associated with energy metabolism, particularly during periods of high milk production or stress, where it can indicate the mobilization of body fat and the subsequent impact on metabolic health. Furthermore, AST levels can be indicative of the health status of dairy cattle, particularly in relation to conditions like subclinical ketosis and hyperketonemia, which are common metabolic disorders in the postpartum period.