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Rabbit Anti-Vaccinia Virus Fusion Complex Associated Protein OPG095 Polyclonal Antibody

Cat. No.VD7N173

Product TypeVeterinary Antibodies

Size 100 µg

Product Overview

BioVenic rabbit polyclonal antibody is specific for vaccinia virus fusion complex associated protein OPG095. It is affinity purified by protein A.

Specifications

Clonality Polyclonal
Classification Primary Antibody
Clone L16N1
Host Rabbit
Target Species Virus
Species Reactivity Virus
Specificity Vaccinia Virus Fusion Complex Associated Protein OPG095
Isotype IgG
Immunogen Inactivated vaccinia virus
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Proclin 300
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

The vaccinia virus fusion complex associated protein OPG095, also referred to as F12L, is a critical component of the virus's fusion machinery. This protein is integral to the process by which the vaccinia virus fuses with the host cell membrane, allowing the viral core to be released into the cytoplasm. OPG095 is part of the fusion complex that includes other proteins such as H3L and A33R, which together mediate the membrane fusion event essential for viral entry. As a target for antiviral research, OPG095 presents a strategic point of intervention. Disrupting its function could potentially inhibit the fusion process, thereby preventing the virus from entering host cells and initiating infection. The detailed study of OPG095's structure and its interaction with other components of the fusion complex is vital for understanding the molecular mechanisms underlying viral fusion. Insights gained from such research could inform the development of antiviral agents that specifically target the fusion process, offering a new approach to combat the vaccinia virus and related poxviruses.

Target Vaccinia Virus Fusion Complex Associated Protein OPG095
Taxonomy ID 10245
UniProt ID P07612

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Laliberte, Jason P., et al. "The membrane fusion step of vaccinia virus entry is cooperatively mediated by multiple viral proteins and host cell components." PLoS Pathogens 7.12 (2011): e1002446.
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