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Veterinary NGS Development
The advent of next-generation sequencing (NGS) has marked a pivotal turning point in veterinary diagnostics, triggering a revolution in diagnostic technology by furnishing high-throughput and exhaustive genomic analysis. BioVenic uses NGS technology to sequence a wide range of DNA or RNA fragments, expanding the scope of animal disease diagnostic research. We have extensive experience in veterinary NGS development and are committed to promoting the application of NGS technology in the field of veterinary diagnosis.
Benefits of NGS in Veterinary Diagnostics
Comprehensive pathogen detection
By conducting a single test, NGS can pinpoint multiple pathogens, spanning bacteria, viruses, parasites, and fungi. This multifaceted approach furnishes invaluable insights, proving pivotal for disease diagnosis, continual monitoring, and strategic management.
Genetic variant detection
NGS helps identify genetic variants and mutations associated with inherited diseases or tumors. This feature is crucial for early detection and diagnosis of the disease.
Metagenome analysis
The power of NGS extends to examining intricate microbial communities across diverse samples-ranging from gut microbiota to environmental specimens. The metagenomic analysis facilitates the diagnosis of animal pathogenic microorganisms and promotes animal health.
What We Offer?
BioVenic provides a wide range of services in veterinary NGS development, including these presented below.
Veterinary NGS Panel or Kit Development
Our specialization lies in crafting targeted NGS panels or kits that are meticulously designed to detect and identify specific pathogens, genetic variations, or markers closely associated with a diverse range of veterinary diseases.
Custom NGS Assay Development
Drawing on the expertise of our adept team, we create tailored NGS assays that precisely align with your distinct research or diagnostic requirements. Our approach is marked by flexibility and customization, ensuring that the assays we develop adhere to the benchmarks of quality and performance.
Custom and Bulk Products
Catering to both specific and large-scale needs, we extend a portfolio of custom and bulk products tailored to your unique demands. Leveraging our extensive global supply chain, we ensure prompt delivery of products and services, guaranteeing that you receive what you require, precisely when and where it's needed.
Bioinformatics Analysis
BioVenic not only offers comprehensive veterinary NGS development but also provides an in-depth bioinformatics analysis of NGS data. This analysis encompasses a spectrum of tasks, including sequence alignment, variant calling, functional annotation, and the interpretation of results-ensuring a holistic understanding of the data at hand.
Veterinary NGS Development Process
BioVenic follows a rigorous development process to ensure the quality and reliability of our preclinical veterinary NGS panels or kits. This process involves several key stages as follows.
Requirements Gathering
We discuss closely with our clients to help them identify specific diagnostic requirements, including target pathogens, genetic markers, or diseases of interest, to ensure that the developed panel or kit is consistent with the intended application.
Validation and Quality Control
We provide our clients with rigorous veterinary NGS panel or kit validation and quality control services, including comparisons to gold standard methods and reviews against known reference samples.
Design and Optimization
Our scientists provide NGS panel or kit design and optimization services. This involves careful selection of target regions or genes, primer design, and optimization of sequencing parameters to maximize sensitivity and specificity.
Documentation and Support
BioVenic provides comprehensive documentation, including detailed protocols and guidelines, to facilitate the seamless integration of customers' veterinary NGS panels or kits into laboratory workflows.
Why Choose Us?
With expertise in NGS technology and veterinary applications, BioVenic remains at the forefront of NGS technology.
Our flexible approach ensures that our veterinary NGS panels or kits meet your exact needs, allowing for efficient and accurate results.
We have rich service experience in the development of NGS to the early detection of animal infectious diseases, animal genetic diseases, and common cancers (lymphoma, hemangiosarcoma, osteosarcoma, etc.) in companion animals.
BioVenic, a pioneer in biotechnology, is a leader in NGS for veterinary applications. By harnessing the power of NGS technologies, BioVenic offers comprehensive solutions for disease diagnosis, research, and improving animal health. Please don't hesitate to contact us.
Reference
- Van Borm, Steven, et al. "Next-generation sequencing in veterinary medicine: how can the massive amount of information arising from high-throughput technologies improve diagnosis, control, and management of infectious diseases?." Veterinary infection biology: molecular diagnostics and high-throughput strategies (2015): 415-436.
Veterinary NGS Development FAQs
NGS has emerged as a potent instrument in the realm of diagnosing zoonotic diseases. Through the sequencing of DNA or RNA obtained from samples, NGS can proficiently discern a diverse array of pathogens, encompassing bacteria, viruses, and parasites. This prowess translates into expedited and precise diagnoses, thereby enabling the implementation of apt treatment and management methodologies.
Certainly, NGS holds a pivotal role in comprehending the genetic foundations of inherited conditions in animals. Utilizing comprehensive whole-genome sequencing or precisely targeted gene panels, veterinary experts can discern genetic variations and mutations intricately tied to hereditary ailments. This profound insight not only elevates the precision of diagnostics but also fosters genetic counseling and paves the way for the creation of individualized treatment methodologies, signifying a significant stride forward in the realm of veterinary care.
NGS proves exceptionally adept at identifying infected animals, covering a spectrum of both DNA and RNA viruses. These encompass an array of pathogens, such as the bovine viral diarrhea virus, bovine herpesvirus 1, porcine rotavirus A, porcine parvovirus, transmissible gastroenteritis virus, porcine circovirus 2, hepatitis E virus, and once more, the bovine viral diarrhea virus, etc.
The timeline for developing a custom veterinary NGS panel or kit varies depending on the complexity of the project and specific requirements. However, BioVenic strives to provide efficient turnaround times without compromising quality.