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Feed Prebiotics-Fructo-Oligosaccharides (FOS)
Fructo-oligosaccharides (FOS) or oligofructose are a type of fructans, consisting of a linear chain of fructose units linked by β (2→1) bonds. Typically, FOS contains glucose units at the ends of the chain, also linked by β (2→1) bonds. The degree of polymerization (DP) of FOS is usually less than 10. BioVenic offers a comprehensive range of solutions for the development of FOS prebiotics for animal feed. These solutions encompass production optimization, characterization, evaluation of in vivo and in vitro effects, mechanism studies, and the development of finished products.
Fig. 1 Fructo-oligosaccharides (FOS)1,2
Production and Characterization of FOS Prebiotics
- Production of FOS Prebiotics
There are two methods for the industrial production of FOS, enzymatic or inulin hydrolysis. Our solutions focus on developing more cost-effective production methods, such as utilizing agricultural waste, developing microbial strains, and producing FOS-producing enzymes.
- Characterization of FOS Prebiotics
Our technology platforms offer various techniques to characterize the structure, purity, composition, and function of FOS. These include methylation analysis, DPPH assay, GC-MS, NMR, IR, and more.
In Vitro Study of FOS as Animal Feed Prebiotics
- In Vitro Prebiotic Efficacy of Prebiotic FOS
By studying the effects of FOS on the growth of probiotics, such as lactic acid bacteria, we facilitate research on the in vitro probiotic effects of FOS. We also help determine the appropriate dosage of additives and investigate whether FOS inhibits the growth of harmful bacteria.
- In Vitro Digestion of Prebiotic FOS
The resistance of FOS to gastric juice and various enzymes in the gastrointestinal system is an essential characteristic of prebiotics. Our in vitro digestion models assist in studying the gastrointestinal stability of FOS by simulating digestion with gastric, salivary, pancreatic, and brush border enzymes
- In Vitro Fermentation of Prebiotic FOS
Using fecal or digesta microorganisms as inoculum and FOS as substrate, our in vitro fermentation models help analyze the impact of FOS on the microbiota of the animal digestive tract. Through technologies such as microbiota analysis, fermentation product analysis, and sugar analysis, we obtain valuable insights into the fermentation characteristics of FOS.
In Vivo Evaluation of FOS in Animals
We offer a range of in vivo models for farm animals and companion animals. By combining feed analysis, animal physiology, biochemistry index analysis, animal metabolite analysis, and gut microbial and metabolite analysis, we can assess the effects of FOS from different sources and dosages. Key indicators include growth performance, intestinal health, intestinal microbial composition, structure, product quality, and immune response.
Mechanism Study of Feed Prebiotics FOS
Our solutions enable the investigation of how prebiotics like FOS impact animals through their effects on gastrointestinal microbes and microbial metabolites. We provide animal nutrition and metabolism services that encompass various studies, including high-throughput microbiome, metabolomics, proteomics, and other omics technologies. These studies aid in the development of assays to better understand the mode of action of FOS.
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Feed FOS Prebiotics Development
Our one-stop solution offers development and performance measurement services for FOS probiotic products. Our services provide valuable information for the development of FOS probiotic products, confirm their effects in animal diets, and determine appropriate dosages.
Applications of FOS as Feed Prebiotics
FOS has numerous benefits in animal feed. It promotes the growth of beneficial bacteria, inhibits harmful bacteria, improves nutrient digestion and absorption, enhances the microecological environment, and boosts immunity and production performance in livestock and poultry. See Table 1 for specific application effects of FOS in various animal types.
Table. 1 Application effects of FOS in animal feed
| Animal types | Effects |
|---|---|
| Pigs |
|
| Chickens |
|
| Cattle |
|
| Companion animals |
|
Development Workflow of Feed Prebiotics FOS
Why Choose Us?
One-stop Technology Platform
Our integrated technology platform covers the entire development process of FOS as animal feed prebiotics, providing comprehensive solutions.
Multiple Animal
Models
We offer various in vivo and in vitro animal models to study the effects of FOS prebiotics, enabling a deeper understanding of their impact.
Characterization Technologies
With a wide range of characterization techniques, we can thoroughly analyze the characteristics of FOS, including structure, purity, antioxidant properties, and more.
Our feed prebiotic FOS development solutions focus specifically on animal feed applications. BioVenic provides professional and customized services for FOS production, characterization, in vitro testing, in vivo evaluation, mechanism studies, and finished product development. If you are interested in our solutions, please contact us with your research plan, and we will be pleased to assist you with the appropriate research services.
References
- Image retrieved from Figure 1 "Fructo-oligosaccharides (FOS)" Ibrahim, 2018, used under [CC BY 4.0]. Without modification.
- Ibrahim, Osama O. "Functional oligosaccharides: Chemicals structure, manufacturing, health benefits, applications and regulations." J Food Chem Nanotechnol 4.4 (2018): 65-76.