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Feed Prebiotics-Inulin

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Extraction and Characterization In Vitro Study In Vivo Evaluation Mechanism Study Prebiotics Development Applications Development Workflow Why Choose Us?

Inulin is a naturally occurring polysaccharide found in plant roots and tubers characterized by its unique fructosyl-fructose structure. It belongs to a class of nondigestible oligosaccharides that cannot be broken down by enzymes in the small intestine but instead are fermented by bacteria in the hindgut. BioVenic offers comprehensive solutions for the development of inulin as animal feed prebiotics. Our services include extraction and characterization, in vivo and in vitro evaluations, mechanism studies, and finished product development.

Extraction and Characterization of Inulin Prebiotics

  • Extraction of Inulin Prebiotics

We focus on the extraction and characterization of inulin prebiotics. Inulin is sourced from various plants such as globe artichoke, chicory roots, Jerusalem artichoke tubers, and elecampane. Using our advanced technology platform and techniques like response surface methodology, we optimize the extraction process to maximize yield and quality.

  • Characterization of Inulin Prebiotics

With the help of our multiple in vitro study platforms, inulin can be characterized comprehensively, some of our inulin characterization services are shown in Table. 1.

Table. 1 Some of our inulin characterization services

Items Techniques
Quantification HPLC, MALDI-MS, CE, TLC
Degrees of polymerization (DP) MALDI-MS, NMR, CE, DSC
Surface morphology and microstructure Scanning electron microscopy (SEM)
Size and size distribution Dynamic light scattering (DLS)
Functional groups FT-IR, Raman spectroscopy
Purity UV–Vis spectroscopy analysis
Stability X-ray diffractogram
Antioxidant capacity DPPH and FRAP assays

In Vitro Study of Inulin as Animal Feed Prebiotics

  • In Vitro Prebiotic Efficacy of Prebiotic Inulin

In vitro studies play a vital role in evaluating the prebiotic efficacy of inulin as animal feed. By examining the effect of inulin on the growth and metabolites of probiotics through in vitro culture, such as Lactobacillus, we can assess the prebiotic effects and determine the appropriate dosage for promoting the growth of specific probiotics.

  • In Vitro Digestion and Fermentation of Prebiotic Inulin

Our animal in vitro digestion and fermentation models help study the digestive and fermentation characteristics of inulin during gastrointestinal processes, providing insights into its bioaccessibility.

In Vivo Evaluation of Inulin in Animals

To evaluate the effectiveness of inulin in animals, in vivo experiments become necessary to assess its effects based on different types, dosages, and duration of administration. We offer various in vivo animal models as well as feed analysis, animal metabolite analysis, and omics study platforms. These resources enable researchers to evaluate the digestibility of inulin, its impact on growth, health, and other relevant indicators. Ultimately, these studies help determine the appropriate dosage and feeding methods for specific animals.

Some common assays used in in vivo animal studies of inulin are:

  • Gut microbial flora: DGGE, 16S rRNA sequencing.
  • Metabolites of gut microbial flora: short chain fatty acids (SCFAs), bile acids, etc.
  • Microbial enzymes analysis.

Mechanism Study of Feed Prebiotics Inulin

Understanding the mechanism by which inulin regulates animal nutrition and health is crucial for effective supplementation in animal feed. Our research focuses on examining animal nutritional metabolites, physiological indicators, digestive tract and fecal microbiomes, and metabolomes. By synthesizing this information, we help elucidate the intrinsic mechanisms by which inulin enhances animal nutrition and health.

Feed Inulin Prebiotics Development

We offer one-stop solutions for the development of inulin products suitable for various animal feed applications.

Examples of Inulin feed additives:

  • Acylated inulin: may be beneficial for delivering high concentrations of SCFA to more distal regions of the colon.
  • Inulin nanoparticles: improve the bioavailability of multiple bioactive compounds
  • Inulin microcapsules: may be a potential encapsulation matrix for essential oil.
  • Inulin synbiotics: promote probiotic effects in animals.

Applications of Inulin as Feed Prebiotics

As a feed additive, inulin can affect the growth performance, immune function, disease resistance ability, product quality and other indicators of animals by regulating the growth of gastrointestinal microbiome. Some of the application effects of inulin in pigs, chickens, cattle, and companion animals are shown in Table. 2.

Table. 2 Applications of inulin in animal feed

Animal types Effects
Pigs
  • Reduces weaning-related transition of intestinal microflora by supporting beneficial bacteria such as bifidobacteria and lactobacilli and thereby decreasing intestinal pathogens like Escherichia coli.
  • Reduces diarrhea, mortality and decreases number of pigs shedding the pathogen.
  • Improves bacterial diversity and stabilization of the bacterial community.
Chickens
  • Controls pathogenic bacteria in chickens.
  • Stimulates the performance of young broiler chickens.
Cattle
  • Improves lactation performance and serum lipids by regulating the rumen microbiome and metabolome in dairy cows.
  • Ameliorates subclinical mastitis via regulation of rumen microbial community and metabolites in dairy cows.
Companion animals
  • Manipulates the composition of the intestinal flora.
  • Stimulates gut integrity.
  • Affects nitrogen metabolism.
  • Reduces offensive fecal odor.

Development Workflow of Feed Prebiotics Inulin

Fig. 1 Development workflow of feed prebiotics inulin (BioVenic Original)

Why Choose Us?

Our advanced technology platform enables in-depth analyses of various prebiotic components, including inulin, enhancing your understanding of its structure and function.

We provide diverse animal models and experimental resources to investigate the digestion, fermentation, effects, and mechanisms of inulin in animals.

Our integrated technology platform covers the entire development process, aiding not only in the creation of new inulin feed prebiotic products but also in their evaluation and effectiveness.

With our expertise and resources, BioVenic offers a comprehensive solution to meet your needs for inulin extraction, characterization, in vivo and in vitro effects and mechanisms, and development and evaluation of finished inulin prebiotic products for animal feed. Contact us today for an efficient and effective solution to your feed prebiotic research needs.

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