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Animal Microbiome Metaproteomics Analysis

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Technology Platforms Why Choose Us?

Microbial metaproteomics focuses on studying the composition and changes in microbial proteins, using the proteome as the research object. Proteomics essentially refers to the comprehensive study of protein characteristics on a large scale, including protein expression levels, post-translational modifications, protein-protein interactions, etc. This allows for an overall and comprehensive understanding of microbial population reproduction and metabolism at the protein level. Proteins are the direct embodiment of gene functions. Based on microbial metagenomic data, further research on their corresponding protein composition and functions will enable a more in-depth exploration of the abundance distribution and functional orientation of molecules in microbial populations. Based on metagenomic data, BioVenic gathers protein information from microbial populations in various animal samples using mass spectrometry technology. We investigate the composition and metabolism of microorganisms, unveiling the relationship between microorganisms and animal bodies. We offer cutting-edge customized metaproteomics services to support customers in conducting extensive research on animal intestinal microbial populations, marine biological microbial populations, and microbial populations in animal living environments.

Fig.1 Metaproteomic Data Analysis of Gut Microorganisms. (Long, et al., 2020) Fig.1 Metaproteomic Data Analysis of Gut Microorganisms. 1

Animal Metaproteomics Technology Platforms

  • High-throughput Comparative Proteomic Analysis

High-throughput comparative proteomics is the scientific study of qualitatively or quantitatively analyzing changes in proteins within the microbiome. BioVenic offers high-throughput quantitative protein expression profiling analysis for comparative proteomics, including iTRAQ/TMT, SILAC, label-free, protein interaction profiling, and other technical services. This solution has been widely used in the field of animal microbiome phenotyping and physiological function analysis.

  • High-throughput Modified Proteomic Analysis

BioVenic conducts comprehensive research on post-translational modifications of animal microbiome proteins and their mechanisms of action. We utilize efficient protein post-translational modification enrichment technology and precise protein quantification methods to achieve quantitative analysis of post-translational modification levels in samples under various physiological conditions. This approach allows us to deeply explore the intricate relationship between fluctuations in post-translational modification levels and life activities. This is a powerful scientific research tool for analyzing the mechanisms of the microbiome affecting animal metabolism, screening biomarkers, identifying disease targets, and developing precise treatments.

  • Animal Metaproteome Data Analysis

BioVenic abandons the use of fixed database selection strategies in current metaproteomic information analysis and, instead, analyzes specific samples based on customer needs. Generally speaking, our data analysis technical experts employ a progressive selection scheme and evaluate the search results from various databases at multiple stages to achieve optimal analysis outcomes.

Objects Goals
Gut/Fecal Microbiome Metaproteomic Analysis Microbiome metaproteomics in animal gut and feces samples.
  • Animal host-microbiota interaction.
  • Animal nutrition and metabolism.
  • Animal disease pathogenesis.
  • Animal immunity.
  • Veterinary diagnostics and therapeutics development.
Rumen Microbiome Metaproteomics Analysis Microbiome metaproteomics in the ruminant rumen.
  • Animal host-microbiota interaction.
  • Animal nutrition and metabolism.
  • Animal disease pathogenesis.
  • Warm house gas emission.
Milk Microbiome Metaproteomics Analysis Microbiome metaproteomics in the milk of lactating agricultural animals.
  • Milk microbiota interaction with host mastitis.
  • Mastitis prevention and treatment development

Why Choose Us?

An integrated system for isolation, characterization, identification, and quantification of animal bile acid metabolomics.

Diversified proteomics services fully cover various types of animal samples to meet a wide range of research needs.

Provide tailored support to clients for advanced bioinformatics data analysis to align with specific research project goals.

BioVenic offers microbial metaproteomics services for a variety of animal samples and research areas related to animal microbiomes. We utilize a blend of automated statistical data analysis platforms and manual proofreading. This combination, along with our accumulated project experience and the guidance and support of experts in various fields, enables us to deliver dependable solutions to our customers. Our goal is to efficiently generate high-quality, publishable data to enhance your research findings. If you encounter any difficulties with animal microbiome metaproteome-related technologies or experimental design, please feel free to contact us.

Reference

  1. Long, Shuping, et al. "Metaproteomics characterizes human gut microbiome function in colorectal cancer." NPJ biofilms and microbiomes 6.1 (2020): 14.
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