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Animal Microbiome Colonization Solutions

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Animal Microbiome Colonization Services Workflow Diagram Microbiome Functions Why Choose Us?

Artificial intervention in the early colonization and maturation of animal microbiomes is an important strategy to optimize livestock health and performance. Feed diet and microbiome management practices greatly influence the gastrointestinal microbiota of farm animals, leading to alterations in nutrient utilization and immune responses. Researchers and farmers utilize human intervention to introduce beneficial microbiota into livestock at an early age. This method is a dependable solution for regulating the animals' digestive metabolism, nutrient absorption, and immunity. BioVenic offers a robust and professional customized service platform for the development of animal microbial colonization programs and exploration of parameters. These services are designed to assist researchers in comprehending the mechanisms of animal-microbiota interactions and the impact of the microbiota on host physiology and pathology. At the same time, we offer valuable scientific support for developing healthy and balanced feeding plans by examining the numerous benefits of introducing or optimizing microbial communities in the gastrointestinal tract of animals.

Fig.1 Microbiome Colonization and Genetic Associations in Calves. (Kouritzin, et al., 2020)Fig.1 Microbiome Colonization and Genetic Associations in Calves. 1

Animal Microbiome Colonization Services

BioVenic offers a range of solutions for the initial microbiome colonization and intestinal development process of animal neonates. These solutions assist researchers in investigating the optimization of parameters related to microbial colonization and the significant impact of the microbiome on animal growth and development.

  • Probiotic Intestinal Colonization Program Development

BioVenic is launching a one-stop service for the early intestinal microbiome colonization of animals. Our expert panel organizes optimal microbiome structures by species and different stages of growth and development, tailoring them to meet client needs. We ensure successful colonization of microbiota and their occupation of specific ecological niches, demonstrating resilience in response to various perturbations.

  • Optimizing Microbiome Community Structure and Stability

BioVenic develops customized services for our clients' scientific research needs, focusing on animal microbiome optimization and community homeostasis. We leverage years of experience in animal omics and microbiology projects to enhance and optimize the imbalanced microbiome, thereby improving the overall development of the gastrointestinal tract in livestock.

Workflow Diagram of Animal Microbiome Colonization Solution

Fig.2 Workflow Diagram of Animal Microbiome Colonization Solution. (BioVenic Original)

Animal Microbiome Functions

Nutrition and Metabolic Function

In addition to synthesizing a variety of amino acids and proteins, intestinal microorganisms also possess metabolic properties that the host itself lacks, enabling them to decompose cellulose in food. Some microorganisms in the intestine can increase the expression of transport proteins that facilitate the transport of small molecule products into cells following decomposition. This symbiotic relationship between intestinal microorganisms and the host greatly improves energy utilization and has a profound impact on the host's nutrition and metabolism.

Immune Function

There is a close communication and collaboration mechanism between intestinal microorganisms and the host immune system. The short-chain fatty acids produced by intestinal microorganisms can be used as energy sources that are absorbed by intestinal epithelial cells and peripheral tissues. This process enables the intestinal barrier to carry out its normal immune functions. Intestinal microorganisms regulate the host's intestinal mucosal immunity in two ways. One way is to enhance the host's intestinal biological barrier and prevent the colonization of pathogenic bacteria. The other way is to stimulate immune cells through its specific components to enhance the host's immune function.

Maintain Intestinal Homeostasis

A healthy intestinal environment is balanced, and stable, and intestinal homeostasis is mainly regulated by intestinal microorganisms. Once the gut microbiota matures, competition between microorganisms and environmental factors can inhibit new microbial colonization and protect against infection. Therefore, intestinal microorganisms play an important role in maintaining intestinal homeostasis. Intestinal microbiota imbalance refers to the disruption of intestinal homeostasis.

Why Choose Us?

Rich experience in animal microbiomics projects and a professional cross-disciplinary omics technology team.

Standardize the microbiome colonization technical process and implement multiple quality controls.

Customized one-stop solutions and precise, efficient project execution.

BioVenic has introduced cutting-edge customized strategies to manipulate microbiome colonization and intestinal development in animals. We design and develop affordable microbiome customization solutions by studying the close connection between the animal microbiome and the host. If you are conducting research related to exploring the animal microbiome and microbiome colonization parameters, please contact us to discuss project details and obtain a quote.

References

  1. Kouritzin, Victoria A., and Le Luo Guan. "The colonization and establishment of the neonatal mammalian microbiome." (2017).
  2. Arshad, Muhammad A., et al. "Gut microbiome colonization and development in neonatal ruminants: Strategies, prospects, and opportunities." Animal Nutrition 7.3 (2021): 883-895.
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