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Animal Nucleotide Metabolomics Analysis
BioVenic offers customers targeted analysis services for crucial metabolic substances. We combine advanced quantitative detection technology platforms with isotope standards to provide precise and dependable data, along with professional analysis reports. We offer robust high-throughput tools for scientific research projects focused on investigating the impact of nucleotides on animal growth, development, reproduction, and inheritance.
Background
Nucleotides are important substances in living organisms, but they are not only precursors for the synthesis of genetic material. Nucleotides have certain regulatory effects on many basic biological processes. The breakdown of adenosine triphosphate (ATP) into energy plays an extremely important role in cellular energy metabolism. Nucleotide derivatives are activated intermediates in many biosynthetic processes. For example, UTP not only participates in glycogen synthesis to supply energy, but also carries and transports glucose.
Fig.1 Schematic Diagram of Mammalian Nucleotide Biosynthesis. 1
Animal Nucleotide Metabolomics Services
- Sample Collection and Preparation
Animal nucleotide sample processing services include sample collection, nucleotide extraction, and pre-treatment prior to detection. Our technical staff relies on their extensive experience in processing animal samples and their excellent professional experimental skills. We ensure that the entire sample preprocessing service is strictly implemented according to a mature preparation system, while also ensuring the integrity of the samples to the greatest extent possible. Our high-quality delivery results also lay a solid foundation for the precision and accuracy of your subsequent instrument detection and analysis.
- Targeted Metabolomics Detection
Our method for detecting animal nucleotide samples with high resolution and sensitivity primarily utilizes UHPLC-MS/MS and GC-MS chromatography tandem mass spectrometry. This allows us to accurately identify and quantify target metabolites even at extremely low concentrations in complex biological samples. According to the specific needs of customers, we conduct qualitative and quantitative analysis of nucleotides and related substances in samples, such as ATP, ADP, AMP, GMP, cAMP, dATP, etc., to speed up the process of the entire scientific research project.
- Analysis and Quantification
For the detection results of the instrument and the preliminary characterization of target metabolites, we provide customers with comprehensive data processing and custom analysis services including statistical analysis and bioinformatics analysis. At the same time, absolute quantification of metabolites is achieved through further mass spectrometry verification and comparison with standards.
Flow Chart of Animal Targeted Metabolomics Analysis Service
Why Choose Us?
Multi-layer optimized and improved targeted metabolomics detection scheme and bioinformatics analysis software.
Design of personalized project solutions guided by a team of experts in genetics and animal metabolism throughout the entire process.
High-precision, specific and sensitive detection technology guaranteed by the combined application of chromatography and mass spectrometry.
Diversified, high-quality and comprehensive delivery results including detection parameters and analysis reports.
BioVenic relies on trace amounts of biological samples to customize qualitative and quantitative analysis of target nucleotide small molecule metabolites in samples for scientific researchers. At the same time, our expert team utilizes advanced bioinformatics analysis systems to deliver valuable information related to metabolism, aligned with the research objectives of our customers. If you are analyzing the biosynthesis, degradation, and function of nucleotides and encountering difficulties in the targeted analysis of specific metabolites, please feel free to contact us to customize the one-stop solution.
Reference
- Lane, Andrew N., and Teresa WM Fan. "Regulation of mammalian nucleotide metabolism and biosynthesis." Nucleic acids research 43.4 (2015): 2466-2485.