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Animal Neurotransmitter Metabolomics Analysis
BioVenic offers customized services of analyzing animal neurotransmitter metabolism for scientific researchers. Our quantitative analysis substances include not only neurotransmitter metabolic molecules but also other neurochemical substances, such as energy metabolites, amino acids, antioxidants, and polyamines. The customized high-sensitivity, high-specificity, and high-throughput quantitative detection services we provide meet the needs of researchers to a greater extent and strongly promote the advancement of animal-related neuroscience research. Combined with biological analysis, it allows researchers expand the scientific research landscape of neurotransmitters in the field of animal physiology, pathology, mechanism of pain, animal behavior, etc.
Background
Neurotransmitters are biologically active chemical messengers that facilitate electrochemical transmission between neurons. Neurotransmitters transmit information from the brain and nervous system to other parts of the body, controlling vital organic functions such as movement, emotional responses, and the body's ability to experience pleasure and pain. Relying on BioVenic's advanced animal sample metabolomics joint detection platform and isotope standard quantitative technology can accurately measure neurochemical substances for multiple research applications.
Fig.1 Schematic Diagram of the Action Mechanism of Two Neurotransmitters in Mice. 1
Animal Neurotransmitter Targeted Metabolomics Services
With the advanced technology platform, professional R&D team, extensive project experience, and mature standardized processes, BioVenic has gained recognition from a majority of scientific research customers for providing customized solutions for animal metabolomics projects. We utilize MRM targeted metabolomics technology, employing LC-MS/MS and UHPLC-MS/MS, to conduct absolute quantitative analysis of numerous neurotransmitter metabolites in animal samples. Of course, to address the technical challenges faced by customers during the application of metabolomics technology, we offer customized solutions for any critical step in the analysis of animal neurotransmitter metabolism.
- Sample Collection and Preparation: standardized animal sample processing procedures for extraction of neurotransmitters.
- Targeted Metabolomics Detection: comprehensive detection platform with high accuracy, specificity, and sensitivity.
- Data Processing and Multi-Dimensional Analysis: conduct quality control, difference analysis, functional analysis, and advanced biochemical analysis according to project requirements.
- Absolute Quantification of Target Metabolites: Multiple classes of neurotransmitter targets.
Flow Chart of Animal Targeted Metabolomics Analysis Service
Classification of Common Neurotransmitters in Animal Organisms
| Biogenic Amines | Amino Acids | Peptides | Others |
|---|---|---|---|
|
Dopamine (DA) Norepinephrine (NE) Adrenaline (A) 5-Hydroxytryptamine (5-HT) |
Gamma-aminobutyric acid (GABA) Glycine Glutamic acid Histamine Acetylcholine (Ach)> |
Endogenous opioid peptide Cholecystokinin (CCK) statin vasopressin Oxytocin Neuropeptide |
Nucleotides Anandamide Nitric oxide (NO)< Carbon monoxide (CO) Anandamide σ receptor |
Why Choose Us?
A comprehensive animal metabolomics targeted detection platform with high accuracy, specificity, and sensitivity.
Covering a variety of animal neurotransmitter targets to fully meet customers' scientific research needs.
Multi-omics correlation and advanced bioinformatics analysis, comprehensive interpretation of data to explore physiological mechanisms.
A team of experts in metabolomics and neurobiology participates in experimental design to achieve one-stop reliable service.
BioVenic has developed a comprehensive and precise solution for detecting and analyzing animal neurochemical substances. This solution enables customers to determine the content of numerous neurotransmitters and related substances in samples simultaneously, using customized and personalized approaches. We have constructed an ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry platform. Our professional technical team combines standard comparison technology and isotope labeling quantitative methods to eliminate interference caused by matrix and concentration differences in the technical process. This allows us to achieve accurate determination of low-concentration neurochemicals from biological samples. We are committed to enabling you to easily apply high-throughput animal metabolomics technology through our solutions for quantitative detection of animal neurotransmitters. This will advance research on neurotransmitter synthesis, neuronal function, and neurological diseases, both in terms of physiology and pathology. Please feel free to contact us and inquire about pricing.
References
- Kim, Kimyeong, and Haejin Yoon. "Gamma-Aminobutyric Acid Signaling in Damage Response, Metabolism, and Disease." International Journal of Molecular Sciences 24.5 (2023): 4584.
- Gasmi, Amin, et al. "Neurotransmitters Regulation and Food Intake: The Role of Dietary Sources in Neurotransmission." Molecules 28.1 (2022): 210.