Animal Amino Acid Metabolomics Analysis

BioVenic specializes in providing customized amino acid metabolomics solutions for scientific researchers interested in studying amino acid levels, metabolic pathways, and biological functions in animals. Through targeted quantitative analysis of a variety of amino acids and derivatives, we support customers to enhance their understanding of the complex relationship between amino acids and metabolism and other personalized needs to extend their understanding of the role of amino acids in animal nutrition and metabolism, animal health and disease development.

Background

Amino acids, as small molecule metabolites, are essential components of proteins. They play a crucial role in stimulating protein synthesis pathways and regulating key metabolic pathways associated with metabolism, growth, and immunity. Amino acids play an essential role in the overall life activities of animals by enhancing digestion, promoting growth and development, and improving health.

Fig.1 Schematic Diagram of Amino Acid Metabolism in Cows. ¹

Animal Amino Acid Metabolomics Services

BioVenic customizes targeted metabolomics end-to-end solutions for animal amino acid metabolism analysis, helping scientific researchers understand the key role played by amino acids in physiological processes. BioVenic has established advanced and efficient analysis processes to achieve a comprehensive analysis of specific amino acids and their metabolic pathways. At the same time, aiming at the scientific research goal of studying and validating biomarkers, we achieve quantitative determination of target metabolites through accurate, sensitive, and mature detection solutions.

• Amino Acid Metabolite Sample Preparation: complete preparation process to avoid interference from peak metabolites.
• Metabolite Detection: LC-MS, GC-MS, NMR, and others.
• Data Analysis: statistical analysis and systematic bioinformatics analysis.
• Absolute Quantification of Targeted Metabolites.
• Customized Analysis.

Flow Chart of Animal Targeted Metabolomics Analysis Service

Applications of Animal Amino Acid Metabolomics Analysis

• Animal Phenotype and Physiological Function

Through rigorous targeted metabolomic analysis with absolute quantification, we conduct an in-depth exploration of the structure and physiological functions of amino acids and their derivatives in hundreds of animal species. An in-depth explanation of the relevant metabolic pathways of amino acid small molecule metabolites and their impact on life activities can help scientific researchers improve the metabolic blueprint more effectively during the growth and development of animals.

• Animal Pathology, Pharmacology and Toxicology

The amino acid metabolism profile of body fluids or tissues can be considered as an important indicator of normal phenotypes, physiological or pathological states. Animals that consume excessive amounts of amino acids such as methionine and arginine develop significant toxicity. Metabolomics and metabolic profiling offer numerous advantages in toxicological assessment, pharmacological studies of amino acid-related diseases, and biomarker discovery. Metabolomic techniques have the potential to explore the mechanisms of homeostatic control and assess how amino acid deficiency or excess disrupts metabolic balance.

• Animal Nutrition and Metabolism

Metabolomic analysis has significantly broadened the research scope of amino acid nutrition. This includes studying the profile and characteristics of dietary amino acids, their metabolism, regulation, and their role in growth, health, and individualized amino acid requirements. This advanced high-throughput technology also holds great promise for refining individualized amino acid requirements and identifying new biomarkers of amino acid nutritional status.

Why Choose Us?

BioVenic offers custom-developed quantitative assays for animal amino acid metabolite profiling services. These assays are designed to assist you in achieving your amino acid metabolism research and biomarker validation goals using precise and well-validated methods. We cater to individual needs across a wide range of research areas in biochemistry, pharmacology, toxicology, metabolic pathways, physiological processes, and more. We customize these areas to fit any specific application. Even if the abundance is low, our high-precision, specific, and sensitive analytical technology ensures accurate analysis of amino acid metabolites. It greatly reduces the interference of high-abundance major metabolites through mature and layer-by-layer optimized sample preparation methods. Don't hesitate to contact us for more information about our services.

References

1. Kim, Jung-Eun, and Hong-Gu Lee. "Amino acids supplementation for the milk and milk protein production of dairy cows." Animals 11.7 (2021): 2118.
2. He, Qinghua, et al. "Metabonomics and its role in amino acid nutrition research." Front Biosci 16 (2011): 2451-2460.