Veterinary Infection Molecular Pathology Services

Equipped with state-of-the-art instruments and staffed by a team of experienced scientists, BioVenic provides comprehensive omics solutions and advanced technological capabilities. Our commitment to advancing animal health through cutting-edge research and innovative technologies positions us as a trusted partner for veterinary professionals, researchers, and organizations. We offer a comprehensive suite of omics solutions, including genomic, transcriptomic, epigenomic and metabolomic analysis, tailored to meet the unique challenges posed by infected animals and pathogens.

Veterinary Infection Molecular Pathology Services

• Molecular Diagnostics Services
  Our molecular diagnostics services are designed to identify and characterize infectious agents in animals. Utilizing advanced techniques such as Polymerase Chain Reaction (PCR), quantitative PCR (qPCR), and next-generation sequencing (NGS), we provide accurate and rapid identification of pathogens, including bacteria, viruses, fungi, and parasites that infect animals.
• ISH and FISH
  In Situ Hybridization (ISH) is a powerful technique used to detect specific nucleic acid sequences within tissue sections. Our ISH and Fluorescent In Situ Hybridization (FISH) services enable the localization of viral, bacterial, or parasitic pathogen genetic material within the context of tissue architecture. Our services enable to detect of multiple targets simultaneously and to measure the pathogen load within tissue samples.
• Biomarker Discovery
  We conduct a global analysis of the genetic determinants contributing to pathogenicity by examining molecular mechanisms of host invasion, immune evasion, and survival strategies. This includes identifying genes that express bacterial toxins, adhesins, and other potential virulence factors that facilitate colonization or cause tissue damage. We support biomarker discovery and validation projects aimed at identifying molecular signatures of animal infection and disease pathology. Our services include metabolomics and proteomics, genomics, epigenomics and transcriptomics analyses combined with digital pathology to uncover genetic variations of pathogens, gene expression profiles in infected tissues, as well as the interaction between animal host and infectious pathogens, to discover novel biomarkers for diagnostic and therapeutic purposes.

Fig.1 Pathogen-driven gene expression patterns can be used in the identification of common therapeutic targets.¹

Platforms and Technologies

Our services are powered by state-of-the-art platforms and technologies, ensuring high accuracy, sensitivity, and throughput. The comprehensive profiling of pathogen quantitation, genetic information and gene expression, and metabolites can provide innovative insight of animal infection pathology and advance veterinary research and development.

• Polymerase Chain Reaction (PCR) and qPCR
• Next-Generation Sequencing (NGS)
• RNA-Seq
• Mass Spectrometry
• Digital Pathology

Applications

Our Veterinary Infection Molecular Pathology Services have wide-ranging applications in animal health and disease research.

• Infectious Disease Diagnosis
  We provide biological reagents and tools to help develop rapid and accurate identification methods of pathogens causing disease in animals.
• Vaccine Development
  Our molecular pathology services enable more efficient evaluation of immune responses to vaccine candidates and enhance the discovery of biomarkers for vaccine efficacy.
• Comparative Pathology
  Our services can be applied in the study of disease mechanisms across different animal species.

Our Advantages

• We utilize the latest technologies and platforms to provide high-quality, reliable, and reproducible results.
• We prioritize our clients' needs, providing personalized project design, detailed reports, and expert consultation to support their research and diagnostic goals.
• Our broad range of services covers all aspects of infection pathology, from molecular diagnostics to histopathology and biomarker discovery.

BioVenic believes that innovation is key to addressing the complex challenges of infectious diseases in animals. Our multidisciplinary approach, combining genomics, transcriptomics, epigenomics, metabolomics, and bioinformatics, ensures that we can provide comprehensive and actionable insights. Please contact us to gain access to the latest advancements in molecular biology for your animal infection pathology.

Reference

1. Hossain, Mohammad Uzzal, et al. "Pathogen-driven gene expression patterns lead to a novel approach to the identification of common therapeutic targets." Scientific Reports 12.1 (2022): 21070.