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Feed Additive Development for Mycotoxins

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Mycotoxin Analysis Adsorbing Efficacy Probiotics Additives Development Enzyme Additives Development Animal Study Product Development Service Workflow Common Feed Additives for Mycotoxins Why Choose Us?

Feed additives used for mycotoxins are substances that can inhibit or lessen the absorption, enhance the excretion of mycotoxins, or alter their mechanisms of action. These additives may work by reducing the availability of mycotoxins, breaking them down, or converting them into less harmful forms. BioVenic offers a comprehensive solution for developing feed additives for mycotoxins, incorporating mycotoxin analysis, safety and efficacy studies, as well as in vitro and in vivo experiments on animals.

Animal Feed Mycotoxin Analysis

In conducting animal feed mycotoxin analysis, a range of methodologies are employed to address the distinct characteristics of each mycotoxin type. Our solutions for animal feed mycotoxin analysis provide precise and streamlined testing services catering to a wide array of mycotoxin varieties. These solutions encompass mycotoxin analytical techniques like ELISA, LFDs, GC, HPLC, and others.

Mycotoxin-Adsorbing Efficacy Evaluation

To evaluate the effectiveness of mycotoxin adsorption, diverse inorganic adsorbents-such as hydrated sodium calcium aluminosilicate, zeolites, bentonites, clays, and activated carbons-are tested and utilized as mycotoxin-adsorbing agents. Other options include components of yeast cell walls, synthetic polymers like cholestyramine and polyvinylpyrrolidone, humic substances, and dietary fibers. Our solutions aid in investigating their adsorbing efficacy under varied conditions.

Probiotics Additives Development for Mycotoxins

Certain probiotics have the capacity to reduce mycotoxins in animal feed via biotransformation, thus fostering animal growth and well-being. Our solutions for probiotics development in animal feed facilitate the study of the mitigating effects of bacteria, fungi, yeast, and other additives for mycotoxins.

Enzyme Additives Development For Mycotoxins

Some enzymes accelerate the conversion of mycotoxins into less harmful forms. Our solutions for enzyme feed additives encompass enzyme screening, optimization, recombinant production, and efficacy validation, aiding in the creation of potent feed enzymes to diminish mycotoxin risks to animals.

Animal Study for Development of Feed Additive for Mycotoxins

As various mycotoxins impact animal species differently, the effects of feed additives developed for these mycotoxins must be verified in animal models. We offer animal in vitro digestion and fermentation models, simulating the digestive and fermentative processes of animals to assess the additive's degradation effects on mycotoxins. Additionally, our in vivo animal models span across a range of species like pigs, poultry, ruminants, and companion animals, to explore the protective effects of feed additives on animals affected by mycotoxins. Analysis services for animal metabolites, biochemical indicators, microbial composition, and more are also provided. Through these animal study solutions, we aid in the development of effective and safe animal feed additives to mitigate the impacts of mycotoxins on animal health.

For more information about our animal study solutions, please visit the following links.

Feed Additive Development for Mycotoxins

In our pursuit of Feed Additive Product Development for Mycotoxins, we specialize in selecting feed additives, formulating them rationally, and verifying their application effects to create products that are both safe and effective. Our focus lies in the practical application efficacy of these products, crafting targeted feed additives tailored to specific animal species or mycotoxins.

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Feed Additive Development Service Workflow

Fig. 1 Feed additive development for mycotoxins service workflow (BioVenic Original)

Common Feed Additives for Mycotoxins

Common feed additives for mycotoxins comprise adsorbing agents, biotransforming agents, and compounds that indirectly affect mycotoxins (e.g., antioxidant agents). The table below outlines the properties of some typical feed additives for mycotoxins along with examples:

Table. 1 Common feed additive for mycotoxins

Type of Additives Descriptions Examples
Mycotoxin-adsorbing agents
  • High molecular weight compounds capable of binding the mycotoxins in contaminated feed without dissociating in the animal's gastrointestinal tract.
  • Can be silica-based inorganic compounds or carbon-based organic polymers
  • Aluminosilicates: bentonites, montmorillonites, zeolite, HSCAS (hydrated sodium calcium aluminosilicate)
  • Activated carbons
  • Yeast cell walls
  • Micronized fibers
  • Bacteria
  • Polymers: cholestyramine, polyvinylpyrrolidone
Mycotoxin-biotransforming agents
  • Biotransforming agents include bacteria, yeast, fungi, and enzymes.
  • Use an enzyme that specifically breaks down the toxin into a non-toxic compound.
  • Bacteria: Nocardia asteroides, Corynebacterium, Mycobacteria, Rhodococcus erythropolis, Flavobacterium aurantiacum
  • Fungi: Aspergillus, Eurotium herbariorum, Rhizopus sp., Penicillium raistricki, Rhinocladiella atrovirens
  • Yeast: Trichosporon mycotoxinivorans, Phaffia rhodozyma, Xanthophyllomyces dendrorhous isolates
  • Enzymes: Protease A, pancreatin, carboxypeptidase A, epoxidase, Lactonohydrolase
Antioxidant agents
  • Some mycotoxins (e.g., AFB1, FB1, OTA, and T2 toxin) are known to cause membrane damage through increased lipid peroxidation.
  • Antioxidants act as superoxide anion scavengers and have been investigated as protective agents against the toxic effects of mycotoxins.
  • Selenium
  • Vitamins: vitamins A, C, and E
  • Natural antioxidants: citrinin, curcumin

Why Choose Us?

Tailored Development Process

We possess comprehensive expertise in developing various types of animal feed additives designed to target mycotoxins, allowing us to customize the development process to meet your specific research requirements.

Diverse Animal
Models

Our in vivo and in vitro animal models encompass a wide array of livestock, poultry, and companion animals, offering valuable benchmarks for the development of feed additives.

State-of-the-Art Technologies

We employ a range of advanced experimental technologies to comprehensively understand the application effects and mechanisms of action of feed additives from multiple perspectives.

With BioVenic's specialized animal feed additive development service focusing on mycotoxins, animal nutrition researchers can engage in mycotoxin analysis, explore the effects of various feed additives in vivo or in vitro, and create mycotoxin-specific feed additive products. If you are intrigued by our solutions, feel free to contact us. We are eager to learn more about your research program and provide effective solutions tailored to your needs.

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