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Feed ANFs-Lectins

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Impacts of Dietary Lectins on Animals Feed Lectin Solutions Service Workflow Why Choose Us?

Lectins, classified as antinutritional factors, are found in feeds sourced from a range of plants. Excessive consumption of lectins by animals can result in diminished growth performance, reduced feed utilization, and compromised immune system functionality, thereby posing a significant threat to the animals' nutrition and health. Through our comprehensive research platform, we provide solutions to address the issue of lectins in animal feed. BioVenic's offerings encompass the detection of lectins, the development of feed additives or biological processes to counteract the adverse effects of lectins on animals, and the facilitation of research into the impact of dietary lectins on animals using in vivo and in vitro models.

Table. 1 Lectin content of some edible plants, compared to their protein content.1

Edible plant Lectin Lectin Content (% of Total Protein)
Lentil (Lens culinaris) LcA 2.5%
Pea (Pisum sativum) PsA 2.5%
Soybean (Glycine max) SBA 2%
Peanut (Arachis hypogaea) PNA 1.5%
Horse gram (Dolichos biflorus) DbA 10%
Kidney bean (Phaseolus vulgaris) PHA 1%
Wheat (Triticum aestivum) WGA 3%
Garlic (Allium sativum) ASA 10%
Black elderberry (Sambucus nigra) SNA-I 3%
Banana (Musa acuminata) Mus a 22.3%

Impacts of Dietary Lectins on Animals

The presence of dietary lectins in a variety of edible plants is a concern (refer to Table 1). Certain lectins can pose health risks to diverse animal species. Given that feed materials are often inadequately heat-processed, the impact of lectins on animal nutrition may be even more pronounced. Because many lectins retain their functional and immunologically active state as they pass through the gut, their interaction with the gut epithelium can harm the digestive system when consumed in high quantities, potentially leading to digestive disorders or diseases in some cases. Table 2 highlights some of the effects of lectins on animals.

Table. 2 Impacts of lectins on animals

Animal Type Impacts
Pigs
  • The inclusion of PHA had a detrimental effect on animal performance, significantly reducing feed intake and daily weight gain.
  • The dietary incorporation of purified soya lectin increased the daily endogenous N flow at the terminal ileum.
Chickens
  • High levels of SBA in diets, along with wheat in the feed, can lead to changes in brush border enzyme activities and jejunal mucosa in chicks.
  • SBA present in raw full-fat soybean may contribute to the runting and stunting syndrome in broiler chickens by binding to and incorporating into enterocytes, associated with intestinal epithelium hyperplasia and dysplasia.
Fishes
  • SBA binds to the intestinal epithelium of fish in vivo, playing a contributory role in pathological changes linked to fish feeds with high soybean protein content.
  • Soybean lectins and trypsin inhibitors impact the weight gain of rainbow trout.

Feed Lectin Solutions

Our feed lectin solutions are designed to analyze samples for the presence of lectins and to develop feed additives or biological processes that mitigate the effects of feed lectins on animal performance and health.

  • Lectin Analysis Solutions

Our Feed Anti-Nutritional Factor (ANF) Analysis services aid in determining the biological properties and primary structure of lectins, along with methods for analyzing lectins in animal feed. Common methods for detecting lectins include ELISA and hemagglutination assays. More specific or sensitive detection may be achieved using enzyme-linked lectin assays (ELLA) or chromatographic techniques. We not only assist in detecting lectins but also help develop innovative methods to analyze lectins from various sources.

  • Feed Additive Development to Mitigate Lectin-Induced Adverse Effects

Our Feed Additive Development for ANFs solutions facilitate the development and assessment of feed additives, including probiotics and prebiotics, to counteract the negative impacts of lectins. Through our services, the effects of various feed additives on animal growth performance and health in the presence of lectins can be assessed using in vivo or in vitro models. We also aid in formulating feed additives to enhance the efficacy of individual components.

  • Biological Methods for Lectin Reduction in Animal Feed

Traditional high-heat methods commonly used to deactivate lectins in feed require substantial energy consumption. In contrast, biological approaches such as enzyme treatments or fermentation provide eco-friendly alternatives for reducing lectin activity and enhancing feed quality. Our comprehensive Feed Biological Processing Development for ANFs solution supports animal nutrition researchers in developing biological techniques to eliminate feed lectins. We assist in optimizing enzyme treatments, microbial strains, and fermentation processes, utilizing assays and animal models to evaluate the efficacy of these methods in removing lectins from feed.

  • Animal Studies on the Impact of Lectins

Our array of animal in vitro and in vivo models, including fermentation and digestion models, enable comprehensive studies on the effects of varying dietary lectin levels on animals and the mechanisms underlying their impact on animal health. These platforms support the exploration of new feed additives and biological treatments. Leveraging our high-throughput omics research platform provides a holistic understanding of animal research related to feed lectins.

For more information about our animal studies, please visit the following links.

Service Workflow of Feed Lectins Solution

Fig. 1 Service workflow of feed lectins solution (BioVenic Original)

Why Choose Us?

Our state-of-the-art feed testing platforms excel in both qualitative and quantitative analysis of various feed components, encompassing traditional nutrients and anti-nutritional factors. We offer cutting-edge solutions for devising innovative testing methodologies specifically tailored for lectins.

Our diverse animal models span livestock, poultry, companion animals, and more, featuring in vivo, in vitro fermentation, and in vitro digestion models. These models serve as invaluable tools for researchers exploring the application effects and underlying mechanisms associated with feed interventions.

We provide animal nutrition researchers with a broad array of products and service platforms dedicated to addressing feed lectin challenges. Our goal is to collaboratively develop strategies that alleviate the repercussions of lectins on animal health, leveraging our expertise and resources.

Understanding the profound impact of lectins in feed on animal well-being and productivity, we are unwavering in our dedication to utilizing advanced products and technologies to aid researchers in counteracting the adverse effects of lectins in animal diets. BioVenic's ANFs-Lectins solutions encompass a wide-ranging array of services, from lectin detection to assisting in feed additive development and optimizing feed bioprocesses. If you are intrigued by our ANFs-Lectins solutions, feel free to contact us to initiate further discussions.

Reference

  1. Barre, Annick, et al. "Are dietary lectins relevant allergens in plant food allergy?." Foods 9.12 (2020): 1724. Under Open Access license CC BY 4.0, without modification.
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