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Feed ANFs-Phenolic Compounds
Phenolic compounds, well-recognized phytochemicals present in all plants, encompass a range of components including simple phenols, benzoic and cinnamic acids, coumarins, tannins, lignins, lignans, and flavonoids. While certain phenols can offer benefits when utilized correctly, others like tannins and cotton phenols in animal feeds not only impact feed palatability but also have adverse effects on animal performance, reproduction, and product quality. At BioVenic, our solutions address phenolic compounds that could negatively impact animals through analytical testing and animal studies. These solutions aid animal nutrition researchers in devising effective nutritional strategies, including feed additives and biological processing to counteract the antinutritional effects of phenolic compounds.
Key Antinutritional Phenolic Compounds
The diverse array of phenolic compounds exerts varying effects on animal health and growth. Some phenolics possess antioxidant properties that combat oxidative stress, while others contribute to gut health improvement and product enhancement. Phenolic compounds like resveratrol, anthocyanins, tea polyphenols, flavanols, and chlorogenic acid are beneficial for human and animal health. Conversely, phenols such as tannins, gossypols, and lignins act as antinutritional factors in feed, impeding nutrient digestion and absorption.
Tannins
Condensed tannins, pivotal antinutritional factors in plant-based feed for monogastric animals, hinder nutrient bioavailability by forming insoluble complexes with feed starch and protein. This diminishes feed palatability and nutrient absorption, and tannins may also interact directly with taste receptors to inhibit animal feeding.
Lignin
Lignin, a complex aromatic polymer present in the secondary cell walls of vascular plants, is an antinutritive element in forages within animal nutrition. It resists fermentation by rumen microbes, undermining its nutritional value.
Gossypols and Derivatives
From cotton seeds, shells, kernel powder, meal, and related by-products, gossypols are present in the form of free (FG) and bound (BG) gossypol. FG negatively impacts male animal fertility by disrupting testicular epithelium, while BG disturbs normal physiological functions and diminishes product quality. When included in feed, FG not only affects animals but also transfers to humans through livestock products.
Fig. 1 Basic structures of phenolic acids and flavonoids1,2
Feed Phenolic Compound Solutions
For phenolic antinutritional factors in feed, our solutions include detection and analysis technologies, feed additive development technologies, feed biological processing development, and animal study solutions to meet the needs of animal nutrition researchers.
- Analytical Solutions for Phenolic Compounds
Utilizing techniques like High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and mass spectrometry, we offer precise quantification of phenolic compounds. Additional methods such as spectrophotometric assays, paper chromatography (PC), thin-layer chromatography (TLC), and capillary electrophoresis (CE) are employed for customized analytical services, aiding in extraction, identification, and quantification of various phenolic antinutritional factors. Our Feed Anti-Nutritional Factor (ANF) Analysis services extend to developing innovative assays for analyzing phenolic compounds across diverse samples.
- Development of Feed Additives to Counteract Phenolic Compounds
Given the detrimental impact of phenolic compounds on animals and the potential threat to economic returns in animal farming, the creation of new feed additives becomes imperative. Our solution encompasses feed additive development, safety evaluations, efficacy assessments, and end-product development. This holistic approach supports researchers in crafting feed additives specifically targeting phenolic antinutritional factors, thereby mitigating adverse effects and enhancing animal growth and product quality.
- Biological Approaches for Phenolic Compound Reduction in Animal Feed
Detoxification strategies aimed at mitigating antinutritive phenolic compounds in animal feed vary based on phenolic compound types, comprising physical, chemical, and biological methods. Biological interventions involve enzymatic processing and microbial fermentation. We aid in devising novel biological techniques leveraging enzymes and microorganisms to detoxify harmful phenolic compounds in animal feed. Our biological feed processing development solutions for ANFs include enzyme and microorganism development, enzymatic degradation processes, microbial feed fermentation processes and optimisation of biological detoxification methods.
- Animal Studies Investigating Phenolic Compounds' Impact
Our in vitro and in vivo animal models facilitate the examination of antinutritive phenolic compounds' effects on animals. Through the in vitro digestion model, researchers delve into how phenolic compounds influence animal digestive functions like nutrient digestibility. The in vitro fermentation model aids in studying microbial actions on phenolic compounds within the animal digestive tract. Leveraging in vivo animal experiments and nutrient metabolite assays, we explore the safety implications of phenolic compounds along with the effects of feed additives or biologically treated feeds.
For more information about our animal studies, please visit the following links.
Service Workflow of Feed Phenolic Compounds Solution
Why Choose Us?
At the forefront of animal nutrition and feed advancements, we dedicate ourselves to delivering innovative products and technologies that meet the evolving needs of our customers.
Leveraging our extensive project background in animal nutrition, we offer a diverse array of animal models and testing services tailored specifically for assessing phenolic antinutritional factors in feed.
Customer research requirements are our priority, and we diligently match these needs with suitable solutions to streamline the research process effectively.
Factors such as specific phenolic compounds serve as crucial elements impacting the efficacy of plant-based feeds. BioVenic's solutions are crafted to offer comprehensive technical support and services targeting common phenolic antinutritional factors. Through our feed analysis, animal nutritional metabolite assessments, and in vivo and in vitro animal modeling tools, we assist in the development of innovative feed additives and bioprocesses. This approach aims to minimize the adverse effects of phenolic compounds on animal well-being and optimize feed resource utilization. For those keen on exploring our solutions, feel free to contact us, and our team will promptly provide you with the necessary information and assistance.
References
- Image retrieved from Figure 1 "Basic structures of phenolic acids and flavonoids." Khoddami et al., 2013, used under [CC BY 3.0]. Without modification.
- Khoddami, Ali, Meredith A. Wilkes, and Thomas H. Roberts. "Techniques for analysis of plant phenolic compounds." Molecules 18.2 (2013): 2328-2375.