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Feed Probiotics-Yeasts
Yeasts are unicellular, eukaryotic microorganisms that fall under the fungi kingdom. They are classified as facultative anaerobes, meaning they can survive and grow with or without the presence of oxygen. For over a century, yeasts and yeast derivatives have been used as feed for animals. At BioVenic, we provide a comprehensive solution for the development of yeasts as feed probiotics. Our solution encompasses strain development, safety and efficacy assessment, yeast fermentation solutions, quality control, and the development of finished probiotic yeast products.
Fig.1 Microscopic observation of Saccharomyces boulardii cells1,2
Strain Development for Probiotic Yeasts
- Yeasts Isolation and Identification
We offer services to develop culture media suitable for yeast isolation and identification. Our solutions employ various experiments, including morphological and biochemical analyses, as well as molecular methods such as DNA sequencing, to identify yeast species accurately.
- Genetic Study on Yeasts
Our Genetic Study on Yeasts aids in deepening the understanding of probiotic yeasts. Through genome sequencing, phylogenomic studies, and comparative genomics research, we can get better understanding of probiotic yeasts of interest and enable the development of enhanced probiotic yeasts with genes associated with stress and pH tolerance, adherence, and other probiotic properties. Additionally, by manipulating yeast genetics, we can create strains that express specific enzymes or other nutrients needed by animals, thus expanding the utilization of yeast.
Safety and Efficacy Assessment of Probiotic Yeasts Strains
- Safety Assessment of Yeasts Strains
Our Safety Assessment evaluates yeast strains to ensure their safety as animal feed probiotics. We conduct tests for antibiotic and antifungal resistance, biogenic amine production, and enzymatic activities.
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- In Vitro Efficacy Assessment of Yeasts as Feed Probiotics
We assess the efficacy of feed probiotic yeasts under simulated animal gastrointestinal conditions, including resistance to temperature, low pH, digestive juices, and bile salts. Our evaluation also covers antibacterial activity, auto-aggregation ability, surface hydrophobicity, antioxidant properties, adhesion ability, immunomodulation, and other probiotic efficacy aspects.
- In Vivo Probiotic Effect Study of Yeasts
By utilizing various animal in vivo models and advanced analysis platforms, our researchers study the effects of different yeast strains on different animals. This helps determine the safety, effectiveness, appropriate dosage, and mechanisms of action of yeasts when used as a substitute for livestock antibiotics.
For more information, please visit the following links.
- Animal Nutrition and Metabolism Solution
- Animal Nutrition and Metabolism Analysis
- Omics Solution in Animal Nutrition and Metabolism
Probiotic Yeasts Fermentation Solution
We offer customized fermentation solutions based on yeast strains. These solutions optimize fermentation conditions, monitor stability and viability, and analyze the production of yeast probiotics or related products. Our focus lies in ensuring strain stability and the safety of fermented products throughout the process.
Probiotic Yeast Development
Comprehensive quality control is crucial to guarantee the safety, efficacy, and consistency of the final probiotic yeast products. We provide quality control solutions for all stages, including strain identification, purity and viability testing, genetic stability assessment, and detection of undesired genes, toxins, and contaminants. We help develop different forms of probiotic yeast products tailored to specific needs. Our solutions cover the development, testing, and application studies of these finished products as animal feed additives.
Probiotic Effects of Yeasts on Animals
Yeasts are used as animal feed additives for various purposes, such as enhancing production performance, improving product quality, boosting disease resistance, promoting digestion and intestinal health, and detoxifying mycotoxins.
Table. 1 Effects of some probiotic yeasts on animals3
| Species | Animal Species | Effects |
|---|---|---|
| Saccharomyces cerevisiae | Pigs | Inhibits the proliferation of pathogenic bacteria through effective competition and maintains the balance of intestinal flora so that piglets can obtain more nutrients. |
| Chickens | Increases the production performance of broilers and increases the resistance of chickens to enteric pathogens. | |
| Cattle | Can not only improve performance and immune function, but also reduce nitrogen emission and improve milk quality. | |
| Saccharomyces boulardii | Pigs | Can reduce the colonization and translocation of pathogenic bacteria in the intestinal tract of pigs, increase intestinal IgA secretion, inhibit inflammation, reduce diarrhea and mortality, improve growth performance and meat quality, etc. |
| Chickens | Enhances immunity, reduces intestinal pathogens, increases the intestinal enzyme content, promotes digestion and absorption, enhances antioxidant capacity, reduces the ratio of feed to meat. | |
| Ruminants | Stabilizes the rumen environment, improves digestive enzyme activity, improves immunity and antioxidant capacity, and reduces the diarrhea rate. | |
| Kluyveromyces marxianus | Chickens | Improves the growth performance, blood biochemical index, antioxidant capacity and the intestinal structure of broiler chickens. |
| Cows | Shows promise as a feed additive to detoxify AFB1 and improve DMI and yield of milk components. | |
| Candida utilis | Pigs | Not only improves growth capacity and reduces diarrhea in weaning piglets, but also increases the diversity and abundance of cecum microspores in weaning piglets. |
Feed Probiotic Yeasts Development Workflow
Why Choose Us?
Our research team boasts extensive expertise in animal nutrition, microbiology, and related fields, allowing us to conduct customized research based on your specific needs.
With our integrated technology platform, we leverage a wide range of internal and external resources to address research challenges related to probiotic yeasts as feed additives.
We possess diverse animal models for conducting in vivo experiments on probiotic yeasts, providing valuable reference results for your applications.
BioVenic's in-depth research on probiotic yeasts as animal feed additives, coupled with our state-of-the-art technology platform and extensive product catalog, enables us to offer solutions encompassing strain development, safety and efficacy evaluation, fermentation studies, quality control, and finished product development. If you are interested in our yeast probiotic solutions, please contact us for assistance with your research.
References
- Image retrieved from Figure 1 " Microscopic observation of S. boulardii cells." Hossain et al., 2020, used under [CC BY 4.0]. The original title was changed to "Microscopic observation of Saccharomyces boulardiicells".
- Hossain, Md Nur, et al. "Identification and growth characterization of a novel strain of Saccharomyces boulardii isolated from soya paste." Frontiers in nutrition 7 (2020): 27.
- Pang, Yuanxiang, et al. "Yeast probiotic and yeast products in enhancing livestock feeds utilization and performance: an overview." Journal of Fungi 8.11 (2022): 1191. Under Open Access license CC BY 4.0, selected parts of the original article.