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Veterinary Bacterial Pathogen De Novo Sequencing

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De Novo Sequencing Service Workflow Applications

Veterinary bacterial de novo sequencing plays a pivotal role in identifying and understanding bacterial pathogens that affect various animals, including livestock, companion animals, poultry, and aquatic species. Through advanced sequencing techniques, such as de novo sequencing, veterinary researchers can accurately analyze the genetic composition of bacterial pathogens, aiding in the development of targeted treatments and preventive measures. BioVenic offers one-stop solution for veterinary bacterial pathogen de novo sequencing at our advanced sequencing platforms, allowing for precise identification of pathogenic bacterial strains infecting animals.

Veterinary Bacterial Pathogen De Novo Sequencing Service

Our de novo sequencing begins with bacterial DNA extraction followed by library construction. Subsequently, we employ cutting-edge sequencing platforms. The generated sequences undergo comprehensive data analysis, including bacterial draft map standard analysis, data quality control, genome preliminary assembly, gene structure prediction, identification of repetitive sequences and non-coding RNAs, and gene function annotation. This meticulous workflow ensures accurate and comprehensive insights into the genetic composition of veterinary bacterial pathogens.

Bacterial DNA Extraction

We offer specialized DNA extraction services tailored to various types of animal samples, such as bacterial suspensions, animal tissues, fecal specimens, and blood samples. We customize our approach based on the specific sample type, employing suitable DNA extraction methods and purification methods to guarantee precise and dependable animal pathogenic bacterial DNA extraction for our clients.

Library Construction

Our service processes the pool of infectious bacterial DNA extracted from the animal sample. We ensure thorough and precise preparation of the DNA for sequencing. This crucial step is essential for optimizing the accuracy and reliability of the subsequent de novo sequencing analysis, guaranteeing comprehensive insights into the genetic composition of the bacterial pathogens present in the sample.

De Novo Sequencing

De novo sequencing utilizes high-throughput sequencing technology to sequence veterinary bacterial genomes without a reference. Our service generates accurate data essential for subsequent genome assembly and analysis. By directly sequencing the genome, de novo sequencing provides comprehensive insights into the genetic composition of animal pathogenic bacterial species, aiding in various veterinary research and diagnostic applications.

Data Analysis

After assembling the raw sequence data derived from de novo sequencing, we provide clients with a range of optional analysis projects. We aid clients in performing bioinformatics analyses on the sequence data, including data QC, bacterial draft map, bacterial gene component analysis, bacterial gene function annotation, comparative analysis, evolutionary analysis, etc. We offer custom bioinformation analysis services for specific veterinary research.

Fig.1 Data analysis of bacterial pathogens using de novo sequencing. (BioVenic Original)

Veterinary Bacterial Pathogen De Novo Sequencing Workflow

Fig.2 Veterinary bacterial pathogen de novo sequencing workflow. (BioVenic Original)

Applications

  • Animal-Specific Bacterial Pathogen Virulence Research
    By analyzing the genetic makeup of bacterial pathogens, we aid in understanding their virulence mechanisms, contributing to the development of effective treatments.
  • Veterinary Antimicrobial Resistance Mechanism Studies
    We investigate the genetic basis of drug resistance in animal pathogens, crucial for combating antimicrobial resistance.
  • Animal Pathogenic Bacterial Molecular Markers Discovery
    Through genome analysis, we identify molecular markers associated with pathogenicity, facilitating targeted disease management strategies.
  • Veterinary Vaccine Development
    Our sequencing data informs the development of vaccines tailored to combat specific bacterial pathogens, enhancing animal health and welfare.

BioVenic de novo sequencing service specializes in veterinary bacterial de novo whole-genome sequencing, which involves assembling a genome without the use of a genomic reference. This approach is particularly useful for sequencing novel veterinary bacterial pathogen genomes. Our bioinformatic scientists support clients to choose read length, and read depth for microbial genome assemblies, and provide customized data analysis results. If you have any questions or requirements on custom veterinary bacterial pathogen de novo whole-genome sequencing services, please don't hesitate to contact us.

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